Calhex 231

652973-93-8

CAS-Nr.: 652973-93-8

Englisch Name:: Calhex 231

Synonyma:: Calhex 231;Calhex-231 (Calhex231);Calhex 231 hydrochloride;4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]benzamide;Benzamide, 4-chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-;4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamide hydrochloride

CBNumber:: CB21565173

Summenformel:: C25H27ClN2O

Molgewicht:: 406.95

MOL-Datei:: 652973-93-8.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 42

Calhex 231 Eigenschaften

Schmelzpunkt:: 53-55°C

storage temp.: -20°C Freezer

Löslichkeit: DMSO: soluble15mg/mL, clear

Aggregatzustand: powder

Farbe: white to beige

CAS Datenbank: 652973-93-8

Sicherheit

WGK Germany	3

Calhex 231 Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White Solid

Verwenden

Calhex 231 hydrochloride has been used:

as a calcium-sensing receptor (CaSR) antagonist: to test its impact on hearing in rats
to test its effect on blood pressure levels spontaneous hypertensive rats (SHRs)
to test its effect on acoustic response bias in zebrafish
in Caco-2 cells to test its effect on, overexpression of fibroblast growth factor-23 (FGF-23 )

Biochem/physiol Actions

Calhex 231 is a negative allosteric modulator of the calcium sensing receptor CaSR. Calhex 231 blocks calcium-induced accumulation of inositol phosphate with an IC50 of 0.36 μM.

Calhex 231 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Calhex 231 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 42)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58
BOC Sciences	--	info@bocsci.com	USA	0	65
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
TCI (Shanghai) Chemical Trading Co., Ltd.	021-61109150	sales@tcisct.com	China	31183	58

4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]benzamide
Calhex 231
Calhex 231 hydrochloride
4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamide hydrochloride
Calhex-231 (Calhex231)
Benzamide, 4-chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-
652973-93-8
C25H27ClN2O
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals