HUMAN PAI-1

140208-23-7

CAS-Nr.: 140208-23-7

Englisch Name:: HUMAN PAI-1

Synonyma:: PAIE;PLANH1;Serpine 1;HUMAN PAI-1;PAI-1, MUTANT;Serpin E1 PAI-1;PAI-1, MUTANT, HUMAN;Human SERPINE1 Protein, His Tag;HUMAN PLASMINOGEN ACTIVATOR INHIBITOR-1;Recombinant Mouse Serpine1 Protein, His Tag

CBNumber:: CB2231028

Summenformel:

Molgewicht:: 0

MOL-Datei:: Mol file

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 46

HUMAN PAI-1 Eigenschaften

storage temp.: -20°C

Aggregatzustand: lyophilized powder

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

WGK Germany	2
HS Code	3504009000

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P

Sicherheit

P305+P351+P338

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

HUMAN PAI-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Plasminogen activator inhibitor 1 (PAI-1) human has been used:

as an inhibitor of pro-brain-derived neurotrophic factor (proBDNF) in radioimmunoprecipitation assay (RIPA) in peripheral blood and lymphocytes
to block plasmin activation in mice infected with C. albicans hyphae
to test its effect on neurite growth in neurons

Allgemeine Beschreibung

Plasminogen activator inhibitor 1 (PAI-1) or serine protease inhibitor E1 (SERPINE1) gene is mapped to human chromosome 7q22.1. PAI-1 is produced in hepatocytes, endothelial cells, smooth muscle cells, megakaryocytes, and adipocytes.

Biochem/physiol Actions

Plasminogen Activator Inhibitor 1 (PAI-1) protein belongs to the Serpin superfamily of serine protease inhibitors. It is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and therefore inhibits the fibrinolysis process. PAI is involved in extracellular matrix remodeling and has been implicated in processes like angiogenesis, chemotaxis, ovulation, and embryogenesis. PAI-1 is present in increased levels in various disease states such as a number of cancer forms, obesity and the metabolic syndrome.

HUMAN PAI-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

HUMAN PAI-1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 46)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Wuhan Chemstan Biotechnology Co., Ltd.	15926423062	422450190@qq.com	China	10132	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
AntibodySystem	027-65279366 18162686757	biolab-reagents@atagenix.com	China	9790	58
United States Biological	--	sales@advtechind.com	United States	6106	58

PLASMINOGEN ACTIVATOR INHIBITOR-1, MUTANT, HUMAN
PLASMINOGEN ACTIVATOR INHIBITOR-1, MUTANT, HUMAN, RECOMBINANT
PAI-1, MUTANT
PAI-1, MUTANT, HUMAN
HUMAN PAI-1
HUMAN PLASMINOGEN ACTIVATOR INHIBITOR-1
PAIE
PLANH1
Plasminogen activator inhibitor 1 (PAI-1) human
Plasminogen activator inhibitor, β-migrating endothelial cell-derived type
Serpin E1 PAI-1
Serpine 1
Plasminogen activator inhibitor 1 (PAI-1) human recombinant, expressed in E. coli, >=90% (SDS-PAGE)
Recombinant Human SSERPINE1 Protein, His Tag
Recombinant Mouse Serpine1 Protein, His Tag
Human SERPINE1 Protein, His Tag
140208-23-7