D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
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- CAS-Nr.
- 103404-90-6
- Englisch Name:
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- Synonyma:
- d-α-hydroxyglutaric acid disodium salt;sodiuM 2-hydroxypentanedioate;(r)-2-hydroxypentanedioic acid;Disodium (R)-2-hydroxyglutarate;(2R)-2-Hydroxypentanedioic acid;D-A-HYDROXYGLUTARIC ACID DISODIUM;SodiuM (R)-2-hydroxypentanedioate;D-α-Hydroxyglutaric acid disodium;isodium,(2R)-2-hydroxypentanedioate;D-α-Hydroxyglutaricaciddisodiumsalt
- CBNumber:
- CB2266017
- Summenformel:
- C5H9NaO5
- Molgewicht:
- 172.11
- MOL-Datei:
- 103404-90-6.mol
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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Eigenschaften
- Schmelzpunkt:
- >291°C (dec.)
- storage temp.
- -20°C
- Löslichkeit
- PBS (pH 7.2): 10 mg/ml
- Aggregatzustand
- A crystalline solid
- Optische Aktivität
- [α]/D 8.5±1.5°, c = 1 in NaOH
- Wasserlöslichkeit
- Soluble to 100 mM in water
- BRN
- 5318041
- Stabilität:
- Hygroscopic
- InChIKey
- DZHFTEDSQFPDPP-HWYNEVGZSA-L
Sicherheit
| WGK Germany |
3 |
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| HS Code |
29181990 |
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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
D-α-Hydroxyglutaric Acid (D-2-HG) is an α-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA). It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT), although defects in HOT are not known to be associated with D-2-HGA. Instead, type I D-2-HGA involves mutations in D-2-hydroxyglutarate dehydrogenase, which converts D-2-HG back to 2-KG. Type II D-2-HGA results from gain-of-function mutations in isocitrate dehydrogenase 2, causing it to supplement HOT in converting 2-KG to D-2-HG. In bacteria, this α-hydroxy acid may be synthesized from oxalate and propionyl-coenzyme A by an α-hydroxyglutaric acid synthetase.
Chemische Eigenschaften
Pale Orange Solid
Verwenden
A potential inhibitor of glutamate carboxypeptidase.
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 131)Lieferanten
103404-90-6()Verwandte Suche:
- D-alpha-Hydroxyglutaric acid disodiuM salt >=95% (GC)
- Disodium (R)-2-hydroxyglutarate
- D-α-Hydroxyglutaric Acid (sodium salt)
- D-ALPHA-HYDROXYGLUTARIC ACID DISODIU
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- D-ALPHA-HYDROXYGLUTARIC ACID DISODIUM SALT
- D-A-HYDROXYGLUTARIC ACID DISODIUM
- (r)-2-hydroxypentanedioic acid
- (2R)-2-Hydroxyglutaric Acid Disodium Salt
- Pentanedioic acid,2-hydroxy-, disodium salt, (2R)-
- sodiuM 2-hydroxypentanedioate
- SodiuM (R)-2-hydroxypentanedioate
- D-α-Hydroxyglutaric acid disodiuM salt
- D-α-Hydroxypentanedioic acid disodium salt, 95%
- D-.alpha.-Hydroxyglutaric Acid (sodium salt)
- D-alpha-Hydroxyglutaric Acid Disodium
- disodium:(2R)-2-hydroxypentanedioate
- (2R)-2-Hydroxypentanedioic acid
- isodium,(2R)-2-hydroxypentanedioate
- D-α-Hydroxyglutaric acid disodium
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT USP/EP/BP
- d-α-hydroxyglutaric acid disodium salt
- D-α-Hydroxyglutaricaciddisodiumsalt
- D-3-Hydroxypentanedioic acid disodium salt
- Pentanedioic acid, 2-hydroxy-, sodium salt (1:2), (2R)-
- (2R)-2-hydroxy-Pentanedioic acid sodium salt (1:2)
- D-α-Hydroxyglutaric Acid (sodium salt)
- Pentanedioic acid,2-hydroxy-,disodium salt,(2R)-(9ci)
- 103404-90-6
- C5H6Na2O5
- Peptide Synthesis
- Specialty Synthesis
- Amino Acid Derivatives
- Aliphatics
- Chiral Reagents
- Inhibitors
