BIBF 1202

894783-71-2

CAS-Nr.: 894783-71-2

Englisch Name:: BIBF 1202

Synonyma:: CS-1313;BIBF 1202;Nintedanib-1;Nintedanib-010;Intedanib Impurity A;Nintedanib impurity A;Nintedanib impuritiesA;Nintedanib Impurity N1;Nintedanib impurities26;Nintedanib Carboxylic Acid

CBNumber:: CB22705077

Summenformel:: C30H31N5O4

Molgewicht:: 525.6

MOL-Datei:: 894783-71-2.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 104

BIBF 1202 Eigenschaften

Schmelzpunkt:: >216°C (dec.)

Siedepunkt:: 759.5±60.0 °C(Predicted)

Dichte: 1.331±0.06 g/cm3(Predicted)

storage temp.: Refrigerator

Löslichkeit: Aqueous Base (Slightly, Heated)

pka: 3.94±0.20(Predicted)

Aggregatzustand: Solid

Farbe: Light Yellow to Yellow

Sicherheit

BIBF 1202 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC₅₀ value of 62 nM.

Verwenden

Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.

BIBF 1202 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BIBF 1202 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 104)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14335	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3149	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Arizest(Shanghai)Pharmatech Co., Ltd	+86-021-60753300	3652837972@qq.com	China	220	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 18678586262	info@paynepharm.com	China	1354	58

894783-71-2()Verwandte Suche:

4'-Amino-N-methylacetanilid p-(Dimethoxymethyl)anisol 4-Chlor-1-(dichlormethyl)benzol 1,3,5-Trichlor-2-(chlormethyl)benzol 4-Chlor-3-nitrobenzoesure N-Methyl-N-(4-nitrophenyl)acetamid 1,2-Dichlor-4-(dichlormethyl)benzol N-Methyl-4-nitroanilin 2,4-Dichlor-1-(dichlormethyl)benzol

(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid
Nintedanib impurity A
BIBF 1202
(3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid
Intedanib Impurity A
Nintedanib Carboxylic Acid
Nintedanib-010
Nintedanib-1
CS-1313
Nintedanib impurity 9/Nintedanib Carboxylic Acid/(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl) methylene)-2-oxoindoline-6-carboxylic acid
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, (3Z)-
Nintedanib impurities26
Nintedanib impuritiesA
Nintedanib Impurity 6Q: What is Nintedanib Impurity 6 Q: What is the CAS Number of Nintedanib Impurity 6 Q: What is the storage condition of Nintedanib Impurity 6 Q: What are the applications of Nintedanib Impurity 6
NintedanibImpurity6-13C-d3
(3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenyl-methylene]-2-oxo-indoline-6-carboxylic acid
Nintedanib Impurity N1
Vascular endothelial growth factor receptor|||BIBF-1202|||Inhibitor
894783-71-2
C30H31N5O4