Anti-LIS1 antibody, Mouse monoclonal

Anti-LIS1 antibody, Mouse monoclonal Struktur
CAS-Nr.
Englisch Name:
Anti-LIS1 antibody, Mouse monoclonal
Synonyma:
Anti-LIS1 antibody, Mouse monoclonal
CBNumber:
CB24669403
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Anti-LIS1 antibody, Mouse monoclonal Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous solution

Sicherheit

Anti-LIS1 antibody, Mouse monoclonal Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Monoclonal Anti-LIS1 antibody produced in mouse has been used in protein pulldown assay and immunofluorescence.

Allgemeine Beschreibung

The gene PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) encodes a protein named LIS1 (lissencephaly-1) that forms the α subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase (PAFAH). The gene is mapped to human chromosome 17p13.3.

Biochem/physiol Actions

The heterotrimeric enzyme, platelet-activating factor acteylhydrolase (PAFAH), catalyzes the cleavage of acetyl group at the SN-2 position of platelet-activating factor. The α subunit encoded by the gene PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) interacts with tubulin and affects microtubule dynamics. Mutations in this gene have been linked to Miller–Dieker lissencephaly, a human brain malformation characterized by a smooth cerebral surface and a disordered organization of the cortical layers resulting from a defect in neuronal migration.

Anti-LIS1 antibody, Mouse monoclonal Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Anti-LIS1 antibody, Mouse monoclonal Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 2)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

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