Anti-LIS1 antibody, Mouse monoclonal
- CAS No.
- Chemical Name:
- Anti-LIS1 antibody, Mouse monoclonal
- Synonyms
- Anti-LIS1 antibody, Mouse monoclonal
- CBNumber:
- CB24669403
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-LIS1 antibody, Mouse monoclonal price More Price(1)
Anti-LIS1 antibody, Mouse monoclonal Chemical Properties,Uses,Production
Uses
Monoclonal Anti-LIS1 antibody produced in mouse has been used in protein pulldown assay and immunofluorescence.
General Description
The gene PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) encodes a protein named LIS1 (lissencephaly-1) that forms the α subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase (PAFAH). The gene is mapped to human chromosome 17p13.3.
Biochem/physiol Actions
The heterotrimeric enzyme, platelet-activating factor acteylhydrolase (PAFAH), catalyzes the cleavage of acetyl group at the SN-2 position of platelet-activating factor. The α subunit encoded by the gene PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) interacts with tubulin and affects microtubule dynamics. Mutations in this gene have been linked to Miller–Dieker lissencephaly, a human brain malformation characterized by a smooth cerebral surface and a disordered organization of the cortical layers resulting from a defect in neuronal migration.
Anti-LIS1 antibody, Mouse monoclonal Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-LIS1 antibody, Mouse monoclonal Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |