Human Cathepsin D ELISA

Human Cathepsin D ELISA Struktur
CAS-Nr.
Englisch Name:
Human Cathepsin D ELISA
Synonyma:
Human Cathepsin D ELISA
CBNumber:
CB24670029
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Human Cathepsin D ELISA Eigenschaften

storage temp. 
-20°C
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
RIDADR  UN 3264 8 / PGIII
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H290 Kann gegenüber Metallen korrosiv sein. Korrosiv gegenüber Metallen Kategorie 1 Warnung GHS hazard pictogramssrc="/GHS05.jpg" width="20" height="20" /> P234, P390, P404
Sicherheit
P234 Nur im Originalbehälter aufbewahren.
P390 Verschüttete Mengen aufnehmen, um Materialschäden zu vermeiden.

Human Cathepsin D ELISA Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Allgemeine Beschreibung

This ELISA antibody pair detects human Cathepsin D. Other species not yet determined.

Biochem/physiol Actions

Cathepsin D encoded by CTSD gene, is an aspartyl protease, plays a major role in degradation of intracellular and endocytosed protein, for maintenance of tissue homeostasis and metabolism. Cathepsin D works as an endopeptidase in the acidic environment of lysosomes. Cathepsin D is part of signal transduction and a potential target for various cancer. Increased levels of Cathepsin D is associated with type 2 diabetes. Cathepsin D regulates sphingolipid metabolism and cholesterol trafficking. Genetic variations in Cathepsin D gene is a risk factor for Alzheimer′s disease and neuronal ceroid lipofuscinosis. Cathepsin D is a key marker in atherosclerosis and level of expression is increased in atherosclerotic lesions. Cathepsin D regulates the degradation of advanced glycation end products (AGEs) and impaired activity of cathepsin D results in accumulation of AGEs in photoaged skin. Increased plasma concentration of Cathepsin D causes non-alcoholic steatohepatitis (NASH) leading to hepatic lipid accumulation and inflammation.

Human Cathepsin D ELISA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Human Cathepsin D ELISA Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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