Human Cathepsin D ELISA
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- CAS-Nr.
- Englisch Name:
- Human Cathepsin D ELISA
- Synonyma:
- Human Cathepsin D ELISA
- CBNumber:
- CB24670029
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Human Cathepsin D ELISA Eigenschaften
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H290 |
Kann gegenüber Metallen korrosiv sein. |
Korrosiv gegenüber Metallen |
Kategorie 1 |
Warnung |
src="/GHS05.jpg" width="20" height="20" /> |
P234, P390, P404 |
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Sicherheit |
P234 |
Nur im Originalbehälter aufbewahren. |
P390 |
Verschüttete Mengen aufnehmen, um Materialschäden zu vermeiden. |
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Human Cathepsin D ELISA Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
For research use only. Not for use in diagnostic procedures.
Please refer to the attached
Protocolfor details.
Allgemeine Beschreibung
This ELISA antibody pair detects human Cathepsin D. Other species not yet determined.
Biochem/physiol Actions
Cathepsin D encoded by CTSD gene, is an aspartyl protease, plays a major role in degradation of intracellular and endocytosed protein, for maintenance of tissue homeostasis and metabolism. Cathepsin D works as an endopeptidase in the acidic environment of lysosomes. Cathepsin D is part of signal transduction and a potential target for various cancer. Increased levels of Cathepsin D is associated with type 2 diabetes. Cathepsin D regulates sphingolipid metabolism and cholesterol trafficking. Genetic variations in Cathepsin D gene is a risk factor for Alzheimer′s disease and neuronal ceroid lipofuscinosis. Cathepsin D is a key marker in atherosclerosis and level of expression is increased in atherosclerotic lesions. Cathepsin D regulates the degradation of advanced glycation end products (AGEs) and impaired activity of cathepsin D results in accumulation of AGEs in photoaged skin. Increased plasma concentration of Cathepsin D causes non-alcoholic steatohepatitis (NASH) leading to hepatic lipid accumulation and inflammation.
Human Cathepsin D ELISA Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Human Cathepsin D ELISA Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 1)Lieferanten