BICALUTAMIDE-D4 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Bicalutamide-d
4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (K
i = 12.5 μM; IC
50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.
Chemische Eigenschaften
BICALUTAMIDE-D4 is White Solid
Verwenden
BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0
BICALUTAMIDE-D4 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
