N-ε-Acetyl-L-lysin
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- CAS-Nr.
- 692-04-6
- Bezeichnung:
- N-ε-Acetyl-L-lysin
- Englisch Name:
- N-EPSILON-ACETYL-L-LYSINE
- Synonyma:
- H-LYS(AC)-OH;N-epsilon-acetyllysine;lys(ac);N6-Acetyllysine;N-EPSILON-ACETYL-L-LYS;NSC 102777;LYSINE(AC)-OH;H-L-LYS(AC)-OH;Nε-Ac-L-Lys-OH;Nε-Acetyllysine
- CBNumber:
- CB3308387
- Summenformel:
- C8H16N2O3
- Molgewicht:
- 188.22
- MOL-Datei:
- 692-04-6.mol
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N-ε-Acetyl-L-lysin Eigenschaften
- Schmelzpunkt:
- 250 °C (dec.)(lit.)
- Siedepunkt:
- 323.23°C (rough estimate)
- Dichte
- 1.1793 (rough estimate)
- Brechungsindex
- 1.4500 (estimate)
- storage temp.
- -20°C
- Löslichkeit
- Aqueous Base (Slightly), Water (Slightly)
- Aggregatzustand
- Powder
- pka
- 2.53±0.24(Predicted)
- Farbe
- White
- Wasserlöslichkeit
- Soluble in water (miscible), and 80% acetic acid (50 mg/ml).
- Sensitive
- Hygroscopic
- InChIKey
- DTERQYGMUDWYAZ-ZETCQYMHSA-N
- CAS Datenbank
- 692-04-6(CAS DataBase Reference)
N-ε-Acetyl-L-lysin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-Llysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.
Chemische Eigenschaften
white crystalline powder
Verwenden
N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.
Definition
ChEBI: An N6-acyl-L-lysine where the N6-acyl group is specified as acetyl.
N-ε-Acetyl-L-lysin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-ε-Acetyl-L-lysin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 149)Lieferanten
692-04-6(N-ε-Acetyl-L-lysin)Verwandte Suche:
- N-E-ACETYL-L-LYSINE
- N-EPSILON-ACETYL-L-LYSINE
- H-L-LYS(AC)-OH
- (2S)-6-acetamido-2-amino-hexanoic acid
- LYSINE(AC)-OH
- Nε-Acetyllysine
- Nε-Ac-L-Lys-OH
- N-epsilon-Acetyl-L-lysine,99%
- 6-N-Acetyl-L-lysine-6-N-Acetyl-L-lysine-d8
- (S)-6-acetaMido-2-aMinohexanoic acid
- Nε-Acetyl-L-lysine
- epsilon-Acetyl-L-lysine
- epsilon-N-Acetyllysine
- NSC 102777
- omega-N-Acetyl-L-lysine
- -Acetyl-L-lysine
- Nε-Acetyl-L-lysine≥ 99% (HPLC)
- (2S)-2-amino-6-acetamidohexanoic acid
- L-Lysine, N6-acetyl-
- N-EPSILON-ACETYL-L-LYSINE USP/EP/BP
- N-epsilon-acetyl-laevo-lysine
- lys(ac)
- N6-Acetyllysine
- N-epsilon-acetyllysine
- H-LYS(AC)-OH
- N-EPSILON-ACETYL-L-LYS
- Lysine impurity 23
- Lysine Impurity 10
- Rabbit Anti-Acetylated Lysine antibody
- Mouse Anti-Acetylated Lysine antibody
- 692-04-6
- CH3CONHCH24CHNH2CO2H
- Amino Acids and Peptides
- BioChemical
- Biochemicals and Reagents
- A - H
- Modified Amino Acids
- A - H
- Amino Acids
- Modified Amino Acids
