ML298

ML298 Struktur
1426916-02-0
CAS-Nr.
1426916-02-0
Englisch Name:
ML298
Synonyma:
ML298;CID53393915;ML298 >=98% (HPLC);ML-298,Inhibitor,ML 298,Phospholipase,inhibit;3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide;Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-
CBNumber:
CB34199383
Summenformel:
C22H23F3N4O2
Molgewicht:
432.44
MOL-Datei:
1426916-02-0.mol

ML298 Eigenschaften

storage temp. 
2-8°C
Löslichkeit
DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
Aggregatzustand
powder
Farbe
white to beige

Sicherheit

WGK Germany  3

ML298 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

ML-298 is an inhibitor of phospholipase D2 (PLD2; IC50 = 355 nM). It is selective for PLD2 over PLD1 (IC50 = 20,000 nM). It decreases invasive migration of U87-MG glioblastoma cells when used at a concentration of 10 μM without inducing cytotoxicity.

Verwenden

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2).

Biochem/physiol Actions

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2; IC50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 μM.

ML298 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ML298 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 31)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Career Henan Chemica Co
+86-0371-86658258 15093356674;
laboratory@coreychem.com China 30255 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
+86-18341751992 +86-15382112998
757984502@qq.com China 892 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9709 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
2853530910@QQ.com China 8011 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
sales@rechemscience.com China 2983 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58

  • ML298
  • Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-
  • ML298 >=98% (HPLC)
  • CID53393915
  • ML-298,Inhibitor,ML 298,Phospholipase,inhibit
  • 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide
  • 1426916-02-0
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