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ML298

ML298 structure

CAS No.: 1426916-02-0

Chemical Name:: ML298

Synonyms: ML298;CID53393915;ML298 >=98% (HPLC);ML-298,Inhibitor,ML 298,Phospholipase,inhibit;3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide;Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-

CBNumber:: CB34199383

Molecular Formula:: C22H23F3N4O2

Molecular Weight:: 432.44

MDL Number:

MOL File:: 1426916-02-0.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:09

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ML298 Properties

storage temp.	2-8°C
solubility	DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
form	powder
color	white to beige

SAFETY

Risk and Safety Statements

WGK Germany	3

ML298 price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML1077	ML298 ≥98% (HPLC)	1426916-02-0	5MG	$117	2023-06-20	Buy
Sigma-Aldrich	SML1077	ML298 ≥98% (HPLC)	1426916-02-0	25MG	$371	2023-06-20	Buy
Cayman Chemical	15349	ML-298 ≥98%	1426916-02-0	1mg	$40	2024-03-01	Buy
Cayman Chemical	15349	ML-298 ≥98%	1426916-02-0	5mg	$109	2024-03-01	Buy
Cayman Chemical	15349	ML-298 ≥98%	1426916-02-0	10mg	$195	2024-03-01	Buy

Product number	Packaging	Price	Buy
SML1077	5MG	$117	Buy
SML1077	25MG	$371	Buy
15349	1mg	$40	Buy
15349	5mg	$109	Buy
15349	10mg	$195	Buy

ML298 Chemical Properties,Uses,Production

Description

ML-298 is an inhibitor of phospholipase D₂ (PLD₂; IC₅₀ = 355 nM). It is selective for PLD₂ over PLD₁ (IC₅₀ = 20,000 nM). It decreases invasive migration of U87-MG glioblastoma cells when used at a concentration of 10 μM without inducing cytotoxicity.

Uses

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2).

Biochem/physiol Actions

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2; IC50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 μM.

ML298 Preparation Products And Raw materials

Raw materials

Preparation Products

ML298 Suppliers

Global( 31)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8011	62
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2983	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58

Supplier	Advantage
Career Henan Chemica Co	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Aladdin Scientific	58
Sigma-Aldrich	80
Shanghai EFE Biological Technology Co., Ltd.	58
ShangHai Biochempartner Co.,Ltd	62
Shanghai Rechem science Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58

ML298 Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]- ML298 >=98% (HPLC) CID53393915 ML-298,Inhibitor,ML 298,Phospholipase,inhibit 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide 1426916-02-0