γ-Secretase Inhibitor I - Calbiochem

γ-Secretase Inhibitor I - Calbiochem Struktur
CAS-Nr.
Englisch Name:
γ-Secretase Inhibitor I - Calbiochem
Synonyma:
γ-Secretase Inhibitor I - Calbiochem
CBNumber:
CB34818158
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

γ-Secretase Inhibitor I - Calbiochem Eigenschaften

Sicherheit

γ-Secretase Inhibitor I - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A potent, cell-permeable, reversible γ-secretase inhibitor that preferentially appears to inhibit the secretion of Aβ1-40 (>90%) over Aβ1-42 (~15%). Aβtotal IC50 ~ 15 M; Aβ1-40 IC50 ~ 22 M; Aβ1-42 IC50 >50 M in CHO cells stable transfected with the cDNA encoding βAPP695.

Biochem/physiol Actions

Primary Targetsecretion of Aβ

γ-Secretase Inhibitor I - Calbiochem Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


γ-Secretase Inhibitor I - Calbiochem Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 1)Lieferanten
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Sigma-Aldrich 021-61415566 800-8193336
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