Oxophenarsin

oxophenarsine Struktur
306-12-7
CAS-Nr.
306-12-7
Bezeichnung:
Oxophenarsin
Englisch Name:
oxophenarsine
Synonyma:
Oxarsan;Phenarsen;Brn 3235865;oxophenarsine;Einecs 206-178-8;2-Amino-4-arsenosophenol;Phenol, 2-amino-4-arsenoso-;538-03-4 (Mono-hydrochloride);3-Amino-4-hydroxyphenylarsinoxide;63951-03-1 (Mono-hydrochloride salt)
CBNumber:
CB3907632
Summenformel:
C6H6AsNO2
Molgewicht:
199.04
MOL-Datei:
306-12-7.mol

Oxophenarsin Eigenschaften

Schmelzpunkt:
133°C (rough estimate)
Siedepunkt:
117.4°C
Aggregatzustand
solid
Farbe
Bright-yellow deliquescent powder or white crystals

Sicherheit

Toxizität LDLo orl-mus: 150 mg/kg JPETAB 76,358,42

Oxophenarsin Chemische Eigenschaften,Einsatz,Produktion Methoden

Industrielle Verwendung

Palladium dissolves in hot oxidising acids. Palladium is used as a hydrogenation catalyst, for H2/D2/T2separation and purification as well as a catalyst in the Wacker process. The Wacker process, which facilitates the oxidation of ethylene to acetaldehyde, was the first organopalladium reaction that was applied on an industrial scale.

Sicherheitsprofil

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and As

Enzyminhibitor

This sulfhydryl-reactive arsenical (FW = 199.04 g/mol; CAS 306-12-7), variously named Mapharsen, Ehrlich-5, oxyphenarsine, oxarsan, arsinoxide, 3-amino-4-hydroxybenzenearsenoxide, and 2-amino-4-arsenosophenol, was originally developed by Nobelist Paul Ehrlich as an anti-syphilis drug. (Note: do not confuse this compound with oxophenylarsine, also known phenylarsine oxide). It is now used as an antiprotozomal agent, particularly against Trypanosoma. Oxophenarsine is typically supplied as the hydrochloride (FW = 235.50 g/mol) and is readily soluble in water. (See also Dichlorophenarsine) Target(s): acetyl-CoA acyltransferase; actomyosin ATPase; aldehyde dehydrogenase; alkaline phosphatase; asparagine synthetase; ATPase, rat brain; ATPase, trypanosomal; cathepsin; cholinesterase; deoxyribonuclease; diisopropylfluorophosphatase; γ-glutamyl hydrolase, or pteroylglutamate conjugase; glyceraldehyde-3-phosphate dehydrogenase; a-glycerophosphate oxidase; hexokinase; myosin ATPase; pyrophosphatase; pyruvate decarboxylase; pyruvate oxidase; ribose-5-phosphate isomerase; succinate dehydrogenase; succinate oxidase; urease.

Oxophenarsin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Oxophenarsin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 4)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051
1027@dideu.com China 9923 58

306-12-7(Oxophenarsin)Verwandte Suche:


  • 2-Amino-4-arsenosophenol
  • Oxarsan
  • Phenarsen
  • (3-Amino-4-hydroxyphenyl)arsenous acid
  • 3-Amino-4-hydroxyphenylarsinoxide
  • 538-03-4 (Mono-hydrochloride)
  • 63951-03-1 (Mono-hydrochloride salt)
  • Brn 3235865
  • Einecs 206-178-8
  • oxophenarsine
  • Phenol, 2-amino-4-arsenoso-
  • 306-12-7
  • C6H6AsNO2
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