oxophenarsine
- CAS No.
- 306-12-7
- Chemical Name:
- oxophenarsine
- Synonyms
- Oxarsan;Phenarsen;Brn 3235865;oxophenarsine;Einecs 206-178-8;2-Amino-4-arsenosophenol;Phenol, 2-amino-4-arsenoso-;538-03-4 (Mono-hydrochloride);3-Amino-4-hydroxyphenylarsinoxide;63951-03-1 (Mono-hydrochloride salt)
- CBNumber:
- CB3907632
- Molecular Formula:
- C6H6AsNO2
- Molecular Weight:
- 199.04
- MDL Number:
- MOL File:
- 306-12-7.mol
| Melting point | 133°C (rough estimate) |
|---|---|
| Boiling point | 117.4°C |
| form | solid |
| color | Bright-yellow deliquescent powder or white crystals |
| FDA UNII | QIC740F43H |
oxophenarsine Chemical Properties,Uses,Production
Definition
ChEBI: Oxophenarsine is a substituted aniline.
brand name
Mapharsen (Parke-Davis).
Industrial uses
Palladium dissolves in hot oxidising acids. Palladium is used as a hydrogenation catalyst, for H2/D2/T2separation and purification as well as a catalyst in the Wacker process. The Wacker process, which facilitates the oxidation of ethylene to acetaldehyde, was the first organopalladium reaction that was applied on an industrial scale.
Safety Profile
Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and As
Enzyme inhibitor
This sulfhydryl-reactive arsenical (FW = 199.04 g/mol; CAS 306-12-7), variously named Mapharsen, Ehrlich-5, oxyphenarsine, oxarsan, arsinoxide, 3-amino-4-hydroxybenzenearsenoxide, and 2-amino-4-arsenosophenol, was originally developed by Nobelist Paul Ehrlich as an anti-syphilis drug. (Note: do not confuse this compound with oxophenylarsine, also known phenylarsine oxide). It is now used as an antiprotozomal agent, particularly against Trypanosoma. Oxophenarsine is typically supplied as the hydrochloride (FW = 235.50 g/mol) and is readily soluble in water. (See also Dichlorophenarsine) Target(s): acetyl-CoA acyltransferase; actomyosin ATPase; aldehyde dehydrogenase; alkaline phosphatase; asparagine synthetase; ATPase, rat brain; ATPase, trypanosomal; cathepsin; cholinesterase; deoxyribonuclease; diisopropylfluorophosphatase; γ-glutamyl hydrolase, or pteroylglutamate conjugase; glyceraldehyde-3-phosphate dehydrogenase; a-glycerophosphate oxidase; hexokinase; myosin ATPase; pyrophosphatase; pyruvate decarboxylase; pyruvate oxidase; ribose-5-phosphate isomerase; succinate dehydrogenase; succinate oxidase; urease.
oxophenarsine Preparation Products And Raw materials
Raw materials
Preparation Products
oxophenarsine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9923 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 58 |