HUMAN BMP-2

HUMAN BMP-2 Struktur
CAS-Nr.
Englisch Name:
HUMAN BMP-2
Synonyma:
BMP-2A;HUMAN BMP-2;HUMAN BMP-2A;BMP-2, HUMAN;RECOMBINANT HUMAN BMP-2;BONE MORPHOGENETIC PROTEIN 2;Bone morphogenetic protein 2A;HUMAN BONE MORPHOGENETIC PROTEIN-2;BONE MORPHOGENETIC PROTEINS-2, HUMAN;BONE MORPHOGENETIC PROTEIN 2 (HUMAN)
CBNumber:
CB4219446
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

HUMAN BMP-2 Eigenschaften

storage temp. 
-20°C

Sicherheit

HUMAN BMP-2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

BMP-2 human has been used to study the biological role of BMP-2 on adult renal progenitor cells under in vitro and in vivo conditions.

Allgemeine Beschreibung

The functional form of BMP-2 (bone morphogenetic protein 2) is a 26kDa protein composed of two identical 114 amino-acid polypeptide chains (monomers) linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino-acid signal sequence for secretion, and a 259 amino-acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant human BMP-2 is a 26kDa homodimeric disulfide-linked protein consisting of two identical 115 amino acid chains.

Biochem/physiol Actions

BMP-2 (bone morphogenetic protein 2) is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. During bone repair, it controls the expression of Runt-related transcription factor 2 (Runx2) and Osterix (Osx), thereby enhancing migration, proliferation and osteogenic differentiation of mesenchymal stem cells. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues including lung, liver, spleen, prostate, ovary, and small intestine.

HUMAN BMP-2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


HUMAN BMP-2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 41)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088
3193328036@qq.com China 29797 68
Shanghai Kanglang Biotechnology Co., Ltd. 021-61998208 18217752821
sales@klbio.cn China 9617 58
Absin Bioscience Inc. 021-38015121 15000105423
chenjw@absin.cn China 24734 58
Wuhan Chemstan Biotechnology Co., Ltd. 15926423062
422450190@qq.com China 10132 58
Abmole Bioscience Inc. 021-50967598 02150967598
sales@abmole.cn China 4495 58
Shanghai Yingxin Laboratory Equipment Co., Ltd. 021-021-59178156 17002132182
3146474380@qq.com China 11303 58

  • RECOMBINANT HUMAN BMP-2
  • HUMAN BMP-2
  • HUMAN BMP-2A
  • HUMAN BONE MORPHOGENETIC PROTEIN-2
  • BONE MORPHOGENETIC PROTEIN 2
  • BONE MORPHOGENETIC PROTEIN 2 (HUMAN)
  • BONE MORPHOGENETIC PROTEINS-2, HUMAN
  • BMP-2, HUMAN
  • BMP-2A
  • Bone morphogenetic protein 2A
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