HUMAN BMP-2
- CAS No.
- Chemical Name:
- HUMAN BMP-2
- Synonyms
- BMP-2A;HUMAN BMP-2;HUMAN BMP-2A;BMP-2, HUMAN;RECOMBINANT HUMAN BMP-2;BONE MORPHOGENETIC PROTEIN 2;Bone morphogenetic protein 2A;HUMAN BONE MORPHOGENETIC PROTEIN-2;BONE MORPHOGENETIC PROTEINS-2, HUMAN;BONE MORPHOGENETIC PROTEIN 2 (HUMAN)
- CBNumber:
- CB4219446
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03457106
- MOL File:
- Mol file
HUMAN BMP-2 price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3326 | BMP-2 human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC) | 10μg | $456 | 2024-03-01 | Buy | |
| Alfa Aesar | J67332 | Bone Morphogenetic Protein 2, human | 10microg | $242 | 2023-06-20 | Buy | |
| Alfa Aesar | J67332 | Bone Morphogenetic Protein 2, human | 2micrograms | $106 | 2021-12-16 | Buy | |
| Usbiological | B2553-08W | Bone Morphogenetic Protein 2 | 100ul | $489 | 2021-12-16 | Buy | |
| Usbiological | 354309 | Bone Morphogenetic Protein 2 | 48Tests | $588 | 2021-12-16 | Buy |
HUMAN BMP-2 Chemical Properties,Uses,Production
Uses
BMP-2 human has been used to study the biological role of BMP-2 on adult renal progenitor cells under in vitro and in vivo conditions.
General Description
The functional form of BMP-2 (bone morphogenetic protein 2) is a 26kDa protein composed of two identical 114 amino-acid polypeptide chains (monomers) linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino-acid signal sequence for secretion, and a 259 amino-acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant human BMP-2 is a 26kDa homodimeric disulfide-linked protein consisting of two identical 115 amino acid chains.
Biochem/physiol Actions
BMP-2 (bone morphogenetic protein 2) is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. During bone repair, it controls the expression of Runt-related transcription factor 2 (Runx2) and Osterix (Osx), thereby enhancing migration, proliferation and osteogenic differentiation of mesenchymal stem cells. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues including lung, liver, spleen, prostate, ovary, and small intestine.
HUMAN BMP-2 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN BMP-2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29786 | 68 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 | sales@klbio.cn | China | 9618 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | wulan@absin.cn | China | 24734 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10351 | 58 |
| Abmole Bioscience Inc. | 021-50967598 02150967598 | sales@abmole.cn | China | 4495 | 58 |
| Shanghai Yingxin Laboratory Equipment Co., Ltd. | 021-021-59178156 17002132182 | 3146474380@qq.com | China | 11609 | 58 |