GDC-0077

2060571-02-8

CAS-Nr.: 2060571-02-8

Englisch Name:: GDC-0077

Synonyma:: CPD1573;RG 6114;GDC-0077;RO 7113755;Inavolisib;GDC-0077 (RG6114);GDC-0077 Inavolisib;Inavolisib (GDC-0077);Inavolisib, 10 mM in DMSO;GDC-0077; RG 6114; RO 7113755

CBNumber:: CB43175543

Summenformel:: C18H19F2N5O4

Molgewicht:: 407.37

MOL-Datei:: 2060571-02-8.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 110

GDC-0077 Eigenschaften

Siedepunkt:: 698.0±65.0 °C(Predicted)

Dichte: 1.63±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMSO:110.0(Max Conc. mg/mL);245.47(Max Conc. mM)

pka: 15.89±0.50(Predicted)

Aggregatzustand: Solid

Farbe: Off-white to yellow

InChIKey: SGEUNORSOZVTOL-CABZTGNLSA-N

SMILES: C(N)(=O)[C@@H](NC1C=C2OCCN3C=C(N4[C@H](C(F)F)COC4=O)N=C3C2=CC=1)C

Sicherheit

GDC-0077 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Inavolisib, or GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and inhibits the growth and survival of PI3K-overexpressing tumor cells. The IUPAC name of this compound is (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide.

GDC-0077 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

GDC-0077 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 110)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
Hubei Chuchang Biotech Co., Ltd.	+undefined15623860702	info@chuchangbiotech.com	China	202	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11767	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32435	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.	+86-519-85525359 +86-15995072465	sales@xuanmingchem.com	China	912	58

2060571-02-8()Verwandte Suche:

Testolacton

GDC-0077
Inavolisib
Propanamide, 2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]-, (2S)-
(2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide
GDC-0077; RG 6114; RO 7113755
RO 7113755
RG 6114
CPD1573
Inavolisib (GDC-0077)
GDC-0077 Inavolisib
Apoptosis,RG 6114,RG-6114,Phosphoinositide 3-kinase,Inhibitor,PI3K,Inavolisib,GDC 0077,GDC0077,inhibit
(S)-2-[[2-[(S)-4-(Difluoromethyl)-2-oxo-3-oxazolidinyl]-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]amino]propanamide
Inavolisib (Synonyms: GDC-0077
(S)-2-((2-((S)-4-(Difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide
Inavolisib (RG-6114, RO-7113755)
(S)-2-((2-((S)-4-(Difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide , Inavolisib
Inavolisib, 10 mM in DMSO
(2S)-2-({4-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-9-oxa-3,6-diazatricyclo[8.4.0.02,?]tetradeca-1(14),2,4,10,12-pentaen-12-yl}amino)propanamide
Inavolisib (GDC-0077, RG6114)
GDC-0077 (RG6114)
(2S)-2-({4-[(4S)-4-(difluoromethyl)-2-oxo-1, 3-oxazolidin-3-yl]-9-oxa-3,6-diazatricyclo[8.4.0.02,]tetradeca-1(14),2,4,10,12-pentaen-12-yl}am
2060571-02-8
GDC-0077