ZIMELIDINE DIHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Tan Oil
Weltgesundheitsorganisation (WHO)
Zimeldine, an inhibitor of serotonin uptake, was introduced in
1982 for the treatment of depressive illness. By 1983 its use had been associated
with incidences of hypersensitivity of varying severity and serious neurological
side effects including the Guillain-Barr, syndrome. Following discussions with the
National Board of Health and Welfare of Sweden, the major manufacturer decided
to withdraw the drug on a worldwide basis.
Biologische Aktivität
5-HT re-uptake inhibitor; selective over noradrenalin and dopamine uptake (IC 50 values are 0.33, 8.2 and 12 μ M respectively). Modulates nociception and induces hyperglycemia in vivo , and is an orally active antidepressant.
ZIMELIDINE DIHYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
