Anti-CD3, low endotoxin antibody, Mouse monoclonal

Anti-CD3, low endotoxin antibody, Mouse monoclonal Struktur
CAS-Nr.
Englisch Name:
Anti-CD3, low endotoxin antibody, Mouse monoclonal
Synonyma:
Anti-CD3, low endotoxin antibody, Mouse monoclonal
CBNumber:
CB44669098
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Anti-CD3, low endotoxin antibody, Mouse monoclonal Eigenschaften

storage temp. 
2-8°C
Aggregatzustand
buffered aqueous solution

Sicherheit

Anti-CD3, low endotoxin antibody, Mouse monoclonal Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Allgemeine Beschreibung

The mouse monoclonal antibody OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.

Biochem/physiol Actions

T-cell receptor- CD3 (cluster of differentiation 3) complex including CD3ε, CD3γ and CD3δ play a vital role in inducing early metabolic events that lead to T cell activation. Mutation in CD3ε has been observed in T-B+ NK+ severe combined immunodeficiency (SCID) patients.

Anti-CD3, low endotoxin antibody, Mouse monoclonal Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Anti-CD3, low endotoxin antibody, Mouse monoclonal Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 1)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

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