Anti-CD3, low endotoxin antibody, Mouse monoclonal

CAS No.
Chemical Name:
Anti-CD3, low endotoxin antibody, Mouse monoclonal
Synonyms
Anti-CD3, low endotoxin antibody, Mouse monoclonal
CBNumber:
CB44669098
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-CD3, low endotoxin antibody, Mouse monoclonal Properties

storage temp. 2-8°C
form buffered aqueous solution

Anti-CD3, low endotoxin antibody, Mouse monoclonal price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB4700041 Anti-CD3, low endotoxin antibody, Mouse monoclonal clone OKT3, purified immunoglobulin, buffered aqueous solution 100μG $281 2024-03-01 Buy
Product number Packaging Price Buy
SAB4700041 100μG $281 Buy

Anti-CD3, low endotoxin antibody, Mouse monoclonal Chemical Properties,Uses,Production

Uses

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

General Description

The mouse monoclonal antibody OKT3 recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.

Biochem/physiol Actions

T-cell receptor- CD3 (cluster of differentiation 3) complex including CD3ε, CD3γ and CD3δ play a vital role in inducing early metabolic events that lead to T cell activation. Mutation in CD3ε has been observed in T-B+ NK+ severe combined immunodeficiency (SCID) patients.

Anti-CD3, low endotoxin antibody, Mouse monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-CD3, low endotoxin antibody, Mouse monoclonal Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-CD3, low endotoxin antibody, Mouse monoclonal