FPG PROTEIN

FPG PROTEIN Struktur
78783-53-6
CAS-Nr.
78783-53-6
Englisch Name:
FPG PROTEIN
Synonyma:
fpg protein from escherichia coli;DNA-formamidopyrimidine glycosylase;Fpg Protein from Escherichia coli, Recombinant;Fpg Protein from Escherichia coli >=90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution, >20,000 units/mg protein
CBNumber:
CB4498113
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

FPG PROTEIN Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 26-36
WGK Germany  1

FPG PROTEIN Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Verwenden

Fpg Protein from Escherichia coli has been used for the assessment of DNA oxidative damage using comet assay.

Allgemeine Beschreibung

Fpg contains two domains separated by a flexible hinge.

Biochem/physiol Actions

Fpg is a key enzyme in the DNA base excision repair pathway (BER). It catalyses the excision of a broad spectrum of modified purines. Fpg has both DNA glycosylase activity that removes the mutated base and AP-lyase activity that releases ribose leaving both 5′- and 3′-phosphorylated ends in the DNA. The zinc finger motif at its C-terminus is responsible for the DNA binding and AP-lyase activity. In addition, its N-terminal proline acts as a nucleophile to produce a Schiff base intermediate that is essential for enzyme action.

FPG PROTEIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


FPG PROTEIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 8)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969
sales@tomums.cn China 4698 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44941 58

  • fpg protein from escherichia coli
  • DNA-formamidopyrimidine glycosylase
  • Fpg Protein from Escherichia coli, Recombinant
  • Fpg Protein from Escherichia coli >=90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution, >20,000 units/mg protein
  • 78783-53-6
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