2-Chlor-1-methylpyridiniumiodid
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- CAS-Nr.
- 14338-32-0
- Bezeichnung:
- 2-Chlor-1-methylpyridiniumiodid
- Englisch Name:
- 2-Chloro-1-methylpyridinium iodide
- Synonyma:
- CMPI;Mukaiyama Reagent;2-chloro-1-Methylpyridin-1-iuM iodide;2-CHLORO-N-METHYLPYRIDINIUM IODIDE;2-Chloro-1-methylpyridinium iodide,97%;2-CHLORO-1-METHYLPYRIDINIUM IODIDE FOR S;2-Chloro-1-methylpyr;Epinastine Impurity 17 Iodide;Epinastine Impurity 26 Iodide;Tributyl Phosphate Impurity 10
- CBNumber:
- CB5102028
- Summenformel:
- C6H7ClIN
- Molgewicht:
- 255.48
- MOL-Datei:
- 14338-32-0.mol
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2-Chlor-1-methylpyridiniumiodid Eigenschaften
- Schmelzpunkt:
- 200 °C (dec.) (lit.)
- Dichte
- 1.7949 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Aggregatzustand
- Crystalline Powder and/or Chunks
- Farbe
- Yellow
- Wasserlöslichkeit
- soluble
- Sensitive
- Moisture & Light Sensitive
- Merck
- 14,6301
- BRN
- 3572320
- Expositionsgrenzwerte
- ACGIH: TWA 0.01 ppm
- InChIKey
- ABFPKTQEQNICFT-UHFFFAOYSA-M
- CAS Datenbank
- 14338-32-0(CAS DataBase Reference)
- EPA chemische Informationen
- 2-Chloro-1-methylpyridinium iodide (14338-32-0)
2-Chlor-1-methylpyridiniumiodid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
yellow crystalline solid
Verwenden
2-Chloro-1-methylpyridinium iodide is a reagent in a wide variety of dehydrative coupling reactions. It is also used to form carboxylate esters from acids and alcohols, carboxamides from acids and amines, lactones from -hydroxy acids and carbodiimides from N,N-disubstituted thioureas.
Allgemeine Beschreibung
2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC.
läuterung methode
Purify it by dissolving in EtOH and adding dry Et2O. The solid is washed with Me2CO and dried at 20o/0.35mm. Store it in the dark. Attempted recrystallisation from Me2CO/EtOH/pet ether (b 40-60o) causes some exchange of the Cl substituent by I. The picrate has m 106-107o, and the perchlorate has m 212-213o. [Jones et al. J Am Chem Soc 111 1157 1989, UV and solvolysis: Barlin & Benbow J Chem Soc, Perkin Trans 2 790 1974, Beilstein 20/5 V 405.]
2-Chlor-1-methylpyridiniumiodid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Chlor-1-methylpyridiniumiodid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 286)Lieferanten
14338-32-0(2-Chlor-1-methylpyridiniumiodid)Verwandte Suche:
- 2-Chloro-1-methylpyr
- 2-Chloro-1-MethylpyridiniuM iodide, 97% 25GR
- 1-Methyl-2-chloropyridiniuM iodide
- PyridiniuM, 2-chloro-1-Methyl-, iodide (8CI,9CI)
- 2-Chloro-1-MethylpyridiniuM Iodide, 98.0%(T)
- 2-CHLORO-1-METHYLPYRIDINIUM IODIDE
- N-Methyl-2-chloropyridinium iodide~Mukaiyamas
- N-Methyl-2-chloropyridiniumiodide
- 2-CHLORO-N-METHYLPYRIDINIUM IODIDE (CMPI)
- CMPI 2-CHLORO-1-METHYLPYRIDINIUM IODIDE
- 2-CHLORO-1-METHYLPYRIDINIUM IODIDE 97%
- Pyridinium, 2-chloro-1-methyl-, iodide
- 2-Chloro-1-methylpyridinium iodide(CMPI)
- 2-Chloro-1-methylpyridinium iodide, 98%, for synthesis
- 2-Chloro-1-methylpyridinium Iodide >
- 2-Chloro-1-methylpyridinium iodide, 97%, for synthesis
- 2-Chloro-1-methylpyridinium iodide ISO 9001：2015 REACH
- 2-Chlor-1-methylpyridiniumiodid
- TIANFUCHEM--14338-32-0--2-Chloro-1-methylpyridinium iodide factory price
- 2-Chloro-1-methylpyridinium iodide,97%
- 2-chloro-1-Methylpyridin-1-iuM iodide
- 2-CHLORO-1-METHYLPYRIDINIUM IODIDE FOR S
- CMPI
- 2-CHLORO-N-METHYLPYRIDINIUM IODIDE
- Mukaiyama Reagent
- 2-chloro - 1-methylepyridinium iodide
- Tributyl Phosphate Impurity 10
- Epinastine Impurity 17 Iodide
- Epinastine Impurity 26 Iodide
- 2-Chloro-1-methylpyridine iodide
- 14338-32-0
- C6H7CllN
- C6H7ClIN
- C6H7ClNI
- C6H7NClI
- Heterocyclic Building Blocks
- Halogenated Heterocycles
- Pyridines
- Building Blocks
- Pyridinium Compounds
- Condensation & Active Esterification
- Reagents for Oligosaccharide Synthesis
- Coupling Reactions (Peptide Synthesis)
- Peptide Synthesis
- Pyridinium Compounds
- Reagents for Oligosaccharide Synthesis
- Synthetic Organic Chemistry
- C6Heterocyclic Building Blocks
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- Pyridines
- Heterocyclic Compounds
- Biochemistry
- Condensation & Active Esterification
