Fentoniumbromid

Fentonium Struktur
5868-06-4
CAS-Nr.
5868-06-4
Bezeichnung:
Fentoniumbromid
Englisch Name:
Fentonium
Synonyma:
Z-326;FA-402;Ulcesium;Fentonium;Phentonium;Ketoscilium;[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide;[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide;3-hydroxy-2-phenyl-propionic acid [8-[2-keto-2-(4-phenylphenyl)ethyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester bromide
CBNumber:
CB51178738
Summenformel:
C31H34BrNO4
Molgewicht:
0
MOL-Datei:
5868-06-4.mol

Fentoniumbromid Eigenschaften

Schmelzpunkt:
203-205° (dec); mp 193-194°
alpha 
D23 -5.68° (c = 5 in DMF); D25 -4.7° (c = 5 in DMF)

Sicherheit

Toxizität LD50 in mice (mg/kg): 12.1 i.v.; >400 s.c. and orally (Teotino, Della Bella)

Fentoniumbromid Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Hoelcesium,Zambon,Italy

Manufacturing Process

5.50g (0.02 mol) of p-phenylphenacyl bromide were dissolved in 56 cc of anhydrous acetone previously heated to about 40°C. This solution was added, with stirring, to a solution of 5.70 g (0.02 mol) of 1-hyoscyamine in 43 cc of anhydrous acetone; the reaction solution was maintained at 45°C and stirred for about six hours.
After standing overnight in the refrigerator, the precipitate was collected by filtration and dried in vacuo at 60°C. Yield: 10.2 g; MP = 193°C to 194°C.

Therapeutic Function

Anticholinergic, Spasmolytic

Fentoniumbromid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Fentoniumbromid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • Fentonium
  • FA-402
  • Ketoscilium
  • Phentonium
  • Ulcesium
  • Z-326
  • [8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide
  • [8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide
  • 3-hydroxy-2-phenyl-propionic acid [8-[2-keto-2-(4-phenylphenyl)ethyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester bromide
  • 5868-06-4
  • C31H34BrNO4
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