Ubiquinol Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Ubiquinol is a reduced form of coenzyme Q
10 (CoQ
10; ), which exists in three redox states: fully oxidized (CoQ
10/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol). CoQ
10 acts as an electron shuttle in the electron transport chain
via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome
bc1 complex. CoQ
10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis.
Chemische Eigenschaften
Light Yellow-Orange Solid
benefits
The reduced form of CoQ10, ubiquinol, is a powerful lipid-soluble antioxidant that provides critical antioxidant protection in the lymph and blood throughout the body. Ubiquinol is the only known fat-soluble antioxidant that human cells can synthesize. In its reduced form, ubiquinol coenzyme Q10 plays a significant role in preventing oxidation in both the lipids that make up much of the structure of cellular membranes in cells throughout the body and also in lipoprotein lipids present in circulation. Coenzyme Q10 can also recycle or regenerate other antioxidants such as vitamin E7 and vitamin C. Ubiquinol plays a critical role in mitochondria by protecting mitochondrial membranes and mitochondrial DNA (mtDNA) from free radical damage[1].
Ubiquinol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
