FC 131

606968-52-9

CAS-Nr.: 606968-52-9

Englisch Name:: FC 131

Synonyma:: FC131,FC-131;cyclo(2Nal-Gly-D-Tyr-Arg-Arg);Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]

CBNumber:: CB52550797

Summenformel:: C36H47N11O6

Molgewicht:: 729.83

MOL-Datei:: 606968-52-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 30

FC 131 Eigenschaften

Dichte: 1.45±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml

pka: 9.89±0.15(Predicted)

Aggregatzustand: Powder

Wasserlöslichkeit: Soluble to 2 mg/ml in water

Sicherheit

FC 131 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

C-X-C chemokine receptor 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 (SDF-1) which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. FC 131 is an inhibitor of CXCR4 activation by SDF-1 (IC₅₀ = 4.5 nM) and also blocks HIV-induced cytopathogenicity (EC₅₀ = 73 nM). FC 131 derivatives can be used for imaging CXCR4 and elucidating its function.

Verwenden

Cyclo[3-?(2-?naphthalenyl)?-?L-?alanylglycyl-?D-?tyrosyl-?L-?arginyl-?L-?arginyl] is a CXCR4 antagonist with anti-HIV properties.

FC 131 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

FC 131 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632	sales@reading-chemicals.com	China	15185	58
Creative Peptides		info@creative-peptides.com	United States	6084	56
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919	eric@peptidego.com	China	6347	58

Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
FC131,FC-131
cyclo(2Nal-Gly-D-Tyr-Arg-Arg)
606968-52-9
C36H47N11O6
CXCR4 antagonist.