FC 131

FC 131 구조식 이미지
카스 번호:
606968-52-9
상품명:
FC 131
동의어(영문):
FC131,FC-131;cyclo(2Nal-Gly-D-Tyr-Arg-Arg);Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
CBNumber:
CB52550797
분자식:
C36H47N11O6
포뮬러 무게:
729.83
MOL 파일:
606968-52-9.mol

FC 131 속성

밀도
1.45±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml
산도 계수 (pKa)
9.89±0.15(Predicted)
물리적 상태
가루
수용성
물에 2mg/ml까지 용해됨

안전

FC 131 C화학적 특성, 용도, 생산

개요

C-X-C chemokine receptor 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 (SDF-1) which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. FC 131 is an inhibitor of CXCR4 activation by SDF-1 (IC50 = 4.5 nM) and also blocks HIV-induced cytopathogenicity (EC50 = 73 nM). FC 131 derivatives can be used for imaging CXCR4 and elucidating its function.

용도

Cyclo[3-?(2-?naphthalenyl)?-?L-?alanylglycyl-?D-?tyrosyl-?L-?arginyl-?L-?arginyl] is a CXCR4 antagonist with anti-HIV properties.

FC 131 준비 용품 및 원자재

원자재

준비 용품


FC 131 공급 업체

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