GALANTHAMINE HYDROBROMIDE
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- CAS-Nr.
- 69353-21-5
- Englisch Name:
- GALANTHAMINE HYDROBROMIDE
- Synonyma:
- NIVALIN;nivaline;1990/4/4;NIVALIN, HBR;zocin-6-olhbr;GALANTAMINE HBR;GALANTHAMINE HBR;jilkonhydrobromide;Galantamine N-D3 HBr;Galantamine O-D3 HBr
- CBNumber:
- CB5439816
- Summenformel:
- C17H22BrNO3
- Molgewicht:
- 368.27
- MOL-Datei:
- 69353-21-5.mol
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GALANTHAMINE HYDROBROMIDE Eigenschaften
- storage temp.
- Sealed in dry,Room Temperature
- Aggregatzustand
- White solid
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
T |
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| R-Sätze: |
25 |
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| S-Sätze: |
45 |
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| RIDADR |
UN 2811 6.1/PG 3 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
DF8075000 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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GALANTHAMINE HYDROBROMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
S-Sätze Betriebsanweisung:
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Allgemeine Beschreibung
A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
Clinical Use
Galantamine, which was introduced in 2001, is an alkaloid found in plants of the family Amaryllidaceae, which includes the daffodil (Narcissus
pseudonarcissus) and snowflake (Leucojum aestivum). It is a reversible inhibitor of AChE, but it does not appear to inhibit butyrylcholinesterase.
Because it is a tertiary amine and can cross the blood-brain barrier, it is indicated for treatment of mild-to-moderate AD and dementia. It has
been used outside the U.S. for more than 30 years as an anticurare agent in anesthesia. Galantamine differs from other cholinesterase
inhibitors, because it allosterically binds to nicotinic receptors, giving it a dual cholinergic action.
Stoffwechsel
It is metabolized (75%) by CYP2D6 and
CYP3A4 to afford the normethyl, O-desmethyl, and O-desmethylnormethyl metabolites, along with some other minor metabolites. Unlike tacrine,
galantamine is not associated with hepatotoxicity. Its elimination half-life is 5.7 hours.
GALANTHAMINE HYDROBROMIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
GALANTHAMINE HYDROBROMIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 148)Lieferanten
69353-21-5()Verwandte Suche:
- 1,2,3,4,6,7,7a,11c-octahydro-9-methoxy-2-methyl-benzofuro(4,3,2-efg)(2)benza
- 3,2-efg)(2)benzazocin-6-ol,1,2,3,4,6,7,7a,11c-octahydro-9-methoxy-benzofuro(
- galanthaminehydrogenbromide
- jilkonhydrobromide
- lycoreminehydrobromide
- 5-Methoxy-9-methyl-2,3,3a,3a1,8,9,10,11-octahydro-4-oxa-9-azacycloocta[def]fluoren-2-ol hydrobromide
- GALANTHAMINE HBR
- GALANTAMINE HBR
- GALANTAMINE HYDROBROMIDE
- GALANTHAMIDE HYDROBROMIDE
- NIVALIN
- NIVALIN, HBR
- 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO[3A,3,2-EF][2]BENZAZEPIN-6-OL HYDROBROMIDE
- nivaline
- nivaline(c17pharmaceutical)
- nivaline(pharmaceutical)
- zocin-6-olhbr
- Galanthamine HBr (Galantamine Hydrobromide)
- Benzofuro[4,3,2-efg][2]benzazocin-2-ol,2,3,3a,8,9,10,11,11b-octahydro-5-Methoxy-9-Methyl-, hydrobroMide (9CI)
- Galantamine N-D3 HBr
- Galantamine O-D3 HBr
- Galantamine synthetic for system suitability
- Galantamine natural for system suitability
- 1,2,3,4,6,7,7a,11c-Octahydro-9-methoxy-2-methylbenzofuro[4,3,2-efg]-2-benzazocin-6-ol hydrobromide
- 2,3,3a,8,9,10,11,11b-Octahydro-5-methoxy-9-methylbenzofuro[4,3,2-efg][2]benzazocin-2-ol hydrobromide
- GALANTHAMINE HYDROBROMIDE USP/EP/BP
- 5-Methoxy-9-methyl-2,3,3a,3a1,8,9,10,11-octahydro-4-oxa-9-azacycloocta[def]fluoren-2-ol hydrobromide(Galantamine Hydrobromide)
- Galantamine HydrobromideQ: What is
Galantamine Hydrobromide Q: What is the CAS Number of
Galantamine Hydrobromide Q: What is the storage condition of
Galantamine Hydrobromide
- High purity CAS 69353-21-5 GALANTHAMINE HYDROBROMIDE in stock
- Nootropics Power Galanthamine
- Galanthamine, Hydrobromide - CAS 69353-21-5 - Calbiochem
- 1990/4/4
- 69353-21-5
- 1953-4-4
- C17H21NO3BrH
- Alkaloids
- Alkaloids (Others)
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors by Enzyme
- Enzyme Inhibitors
- Cholinesterase
- A to C
- BioChemical
- Biochemicals and Reagents
- Galantamine
