Megestrol

Megestrol Struktur
3562-63-8
CAS-Nr.
3562-63-8
Bezeichnung:
Megestrol
Englisch Name:
Megestrol
Synonyma:
C07120;Megestro;MEGESTROL;Megestrol USP/EP/BP;megestrol solution,100ppm;Megestrol acetate EP Impurity B;Metesterone acetate EP impurity B;4,6-PREGNADIEN-6-METHYL-17-OL-3,20-DIONE;Megestrol (base and/or unspecified salts);20-dione,17-hydroxy-6-methyl-pregna-6-diene-3
CBNumber:
CB5465978
Summenformel:
C22H30O3
Molgewicht:
342.47
MOL-Datei:
3562-63-8.mol

Megestrol Eigenschaften

Schmelzpunkt:
207-208 °C(Solv: ethyl ether (60-29-7); acetone (67-64-1))
Siedepunkt:
500.4±50.0 °C(Predicted)
Dichte
1.15±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
Löslichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.00±0.70(Predicted)
Farbe
White to Off-White
CAS Datenbank
3562-63-8(CAS DataBase Reference)

Sicherheit

Giftige Stoffe Daten 3562-63-8(Hazardous Substances Data)

Megestrol Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White Solid

Verwenden

Megestrol is an orally active progestogen. Megestrol is used in combinations as oral contraceptive and as antineoplastic agent.

Indications

As a representitive of the compounds of the class of progestins, this drug is used for various forms of cancer, in particular cancer of the breast, kidneys, and others.

Definition

ChEBI: A 3-oxo Delta4-steroid that is pregna-4,6-diene-3,20-dione substituted by a hydroxy group at position 17.

Weltgesundheitsorganisation (WHO)

Megestrol acetate, a synthetic progestogen, was introduced in the early 1960s as a component in oral contraceptive preparations. In 1967, as a result of new regulations required by the United States Food and Drug Administration, megestrol acetate was submitted to long-term toxicity studies and by the early 1970s it was shown to be associated with an increased incidence of mammary tumours in beagle bitches which led to its withdrawal by several regulatory authorities. Subsequently the validity of the beagle bitch model as a predictor of carcinogenicity of steroid contraceptives has been contested by many national regulatory authorities and megestrol remains available in some countries for contraceptive purposes. In other countries its use is restricted to anticancer treatment. (Reference: (WHODI) WHO Drug Information, 1-3, 5-7, 1984)

Megestrol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Megestrol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 151)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387
1057@dideu.com China 3957 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5866 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29888 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14335 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39916 58
Hebei shuoxi biotechnology co. LTD
+8613081092107
CHINA 968 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12446 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Hebei Lihe Biotechnology Co.,ltd
86-311-80292533 13315122300
sales@lihebiotech.com CHINA 305 58

3562-63-8(Megestrol)Verwandte Suche:


  • 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione
  • 20-dione,17-hydroxy-6-methyl-pregna-6-diene-3
  • 4,6-PREGNADIEN-6-METHYL-17-OL-3,20-DIONE
  • 17-ALPHA-HYDROXY-6-METHYL-4,6-PREGNADIENE-3,20-DIONE
  • MEGESTROL
  • 17-alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione
  • Megestrol (base and/or unspecified salts)
  • C07120
  • megestrol solution,100ppm
  • (8R,9S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • Megestrol acetate EP Impurity B
  • Megestrol Acetate Impurity 2(Megestrol Acetate EP Impurity B)(Megestrol)
  • Megestro
  • Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
  • Megestrol Acetate Impurity 2(Megestrol Acetate EP Impurity B)
  • Metesterone acetate EP impurity B
  • Megestrol USP/EP/BP
  • 3562-63-8
  • Hormone Drugs
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • 3562-63-8
Copyright 2019 © ChemicalBook. All rights reserved