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17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat Produkt Beschreibung

Megestrol acetate  Struktur
595-33-5
CAS-Nr.
595-33-5
Bezeichnung:
17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat
Englisch Name:
Megestrol acetate
Synonyma:
S4;MGA;Nia;5071;Megace;MGA-d3;Ovaban;Ovarid;bdh1298;Maygace
CBNumber:
CB9434253
Summenformel:
C24H32O4
Molgewicht:
384.51
MOL-Datei:
595-33-5.mol

17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat Eigenschaften

Schmelzpunkt:
214°C
Siedepunkt:
431.17°C (rough estimate)
alpha 
D24 +5° (chloroform)
Dichte
1.0474 (rough estimate)
Brechungsindex
11 ° (C=2, CHCl3)
storage temp. 
Refrigerator
Löslichkeit
Practically insoluble in water, soluble in acetone, sparingly soluble in alcohol.
Aggregatzustand
neat
Merck 
14,5805
BRN 
1917291
CAS Datenbank
595-33-5(CAS DataBase Reference)
NIST chemische Informationen
Megestrol acetate(595-33-5)
EPA chemische Informationen
Pregna-4,6-diene- 3,20-dione, 17-(acetyloxy)-6-methyl-(595-33-5)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 40-48
S-Sätze: 22-24/25
WGK Germany  3
RTECS-Nr. TU4075000
HS Code  29372390
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H351 Kann vermutlich Krebs verursachen. Karzinogenität Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
H373 Kann die Organe schädigen bei längerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizität (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
Sicherheit
P260 Dampf/Aerosol/Nebel nicht einatmen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P281 Vorgeschriebene persönliche Schutzausrüstung verwenden.

17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R40:Verdacht auf krebserzeugende Wirkung.
R48:Gefahr ernster Gesundheitsschäden bei längerer Exposition.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

Crystalline Solid

Verwenden

Progestogen;Progesterone receptor agonist

Verwenden

Orally active progestogen; formerly used in combinations as oral contraceptive

Trademarks

Megace (Bristol-Myers Squibb); Megace (Par).

Allgemeine Beschreibung

Megestrol acetate, 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate(Megace), is a progestin used primarily for the palliativemanagement of recurrent, inoperable, or metastatic endometrialor breast carcinoma. Megestrol acetate has also beenindicated for appetite enhancement in patients with AIDS.The biochemical basis for this use of megestrol is unclear.

Sicherheitsprofil

Suspected carcinogen with experimental carcinogenic and teratogenic data. Poison by intravenous route. Human reproductive effects bp ingestion and implant routes: effects on ovaries and fallopian tubes, menstrual cycle changes, and female fertility index changes. Mutation data reported. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. An FDA proprietary drug used to treat endometriosis and breast cancer. A steroid.

Veterinary Drugs and Treatments

Megestrol acetate (Ovaban?—Schering) is approved by FDA for use in dogs only for the postponement of estrus and the alleviation of false pregnancy. In male dogs, it has been used for benign prostatic hypertrophy. It is used clinically for many dermatologic and behavior- related conditions, primarily in the cat. See the Dosage section for specific indications and dosages for both dogs and cats.
Megestrol acetate is indicated in humans for the palliative treatment of advanced carcinoma of the breast or endometrium.

17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 252)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21956 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32452 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 25796 58
Hebei Huanhao Biotechnology Co., Ltd.
86-0311-83975816 whatsapp +8618034554576
86-0311-83975816 grace@hbhuanhao.com CHINA 704 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20084 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58

595-33-5(17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat)Verwandte Suche:


  • Megesgtrol Acetate
  • Megestrol Acetate (250 mg)
  • 6-MethleneProgesterone Acetate
  • * Megestrol acetate acetate
  • Megestrol acetate, progesterone
  • 17-(acetyloxy)-6-methylpregna-4,6-diene-3,20-dione
  • Megestrol Acetate (Medroxyprogesterone Acetate EP Impurity G)
  • 17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione
  • 17-alpha-acetoxy-6-dehydro-6-methylprogesterone
  • 17alpha-Acetoxy-6-dehydro-6-methylprogesterone
  • 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione17-acetate
  • 6-methyl-6-dehydro-17-alpha-acetylprogesterone
  • 6-Methyl-6-dehydro-17alpha-acetylprogesterone
  • 6-methyl-delta(sup4,6)-pregnadien-17-alpha-ol-3,20-dioneacetate
  • 6-methyl-delta(sup6)-dehydro-17-alpha-acetoxyprogesterone
  • 6-Methyl-delta4,6-pregnadien-17-alpha-ol-3,20-dione acetate
  • 6-Methyl-delta6-dehydro-17-alpha-acetoxyprogesterone
  • BDH 1298
  • bdh1298
  • component of Co-ervonum
  • component of Delpregnin
  • component of Kombiquens
  • component of Noval
  • component of Nuvacon
  • component of Planovin
  • component of Triu-ervonum
  • component of Volidan
  • component of Weradys
  • Magestin
  • Maygace
  • Megace
  • Megeron
  • Megestat
  • Megestil
  • Megestryl acetate
  • MEGESTROL 17-ACETATE VETRANAL, 100 MG
  • MegestrolAcetateBase
  • 17-(Acetyloxy)-6-methyl-d3-pregna-4,6-diene-3,20-dione
  • BDH 1298-d3
  • DMAP-d3
  • Magestin-d3
  • Magestryl Acetate-d3
  • 5071
  • 6-dehydro-6-methyl-17-alpha-acetoxyprogesterone
  • 6-Dehydro-6-methyl-17alpha-acetoxyprogesterone
  • 6-diene-3,20-dione,17-hydroxy-6-methyl-pregna-acetate
  • 6-Methyl-17-alpha-acetoxypregna-4,6-diene-3,20-dione
  • 6-methyl-17-alpha-hydroxy-delta(sup6)-progesteroneacetate
  • 6-Methyl-17alpha-hydroxy-delta6-progesterone acetate
  • 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate
  • 6-methyl-6-dehydro-17-alpha-acetoxyprogesterone
  • 6-Methyl-6-dehydro-17alpha-acetoxyprogesterone
  • megestrylacetate
  • Nia
  • Niagestin
  • NSC-71423
  • Ovaban
  • Ovarid
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