Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem

Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem Struktur
CAS-Nr.
Englisch Name:
Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem
Synonyma:
Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem
CBNumber:
CB54817827
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem Eigenschaften

Sicherheit

Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable, potent, fast-acting, and selective inhibitor of prolyl oligopeptidase (PREP) (Ki = 23 pM). Reported to cross the blood-brain barrier. Inhibits about 85% PREP activity within 10 minutes of administration and exhibits a half-life of about 4.8 hours. Exhibits higher lipophilicity that increases its penetration across biological membranes in vivo. Maximum plasma and brain levels are achieved within 10 minutes following its i.p. administration. Shown to block oxidative-stress induced α-synuclein aggregation and clearance in cellular and animal models of Parkinson′s disease. Also shown to improve cognitive performance in young rats (1-5 mg/kg) in a dose-dependent manner.

Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 1)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

  • Prolyl Endopeptidase Inhibitor III, KYP-2047 - Calbiochem
Copyright 2019 © ChemicalBook. All rights reserved