ANTI-PHOSPHO-STAT3 (PTYR705)

ANTI-PHOSPHO-STAT3 (PTYR705) Struktur
CAS-Nr.
Englisch Name:
ANTI-PHOSPHO-STAT3 (PTYR705)
Synonyma:
ANTI-STAT3 (PY705);ANTI-PHOSPHO-STAT3 (Y705);ANTI-PHOSPHO-STAT3 (PTYR705);ANTI-STAT3 (PTYR705) MOUSE MAB;ANTI-ACTIVATED STAT3 (TYR 705);ANTI-STAT3 (PHOSPHORYLATED) (PTYR705);Anti-HIES antibody produced in rabbit;Anti-APRF antibody produced in rabbit;Anti-MGC16063 antibody produced in rabbit;Anti-FLJ20882 antibody produced in rabbit
CBNumber:
CB6206002
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-PHOSPHO-STAT3 (PTYR705) Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution

Sicherheit

S-Sätze: 23-24/25
WGK Germany  1

ANTI-PHOSPHO-STAT3 (PTYR705) Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Anti-phospho-STAT3 (pTyr705) antibody produced in rabbit has been used in immunohistochemical staining and immunoblotting.

Allgemeine Beschreibung

Signal transducer and activator of transcription 3 (STAT3) is a member of STAT family and it composed of 770 amino acids. The gene encoding protein consists of 24 exons and is extended over a length of 75170 bases on genomic DNA STAT3 is mapped on human chromosome 17q21.2. The protein is characterized with a conserved amino-terminal domain, a DNA-binding domain, an SH2 domain and a carboxy-terminal transactivation domain.

Biochem/physiol Actions

Signal transducer and activator of transcription 3 (STAT3) plays a vital role in various cellular responses such as induction of an acute-phase response in hepatoma cells, stimulation of proliferation in B lymphocytes, activation of terminal differentiation and growth arrest in monocytes, and regulation of the pluripotency of embryonic stem cells. Activated STAT3 has been involved in malignant transformation. STAT3 may be a key player in the pathogenesis of diverse human cancers which makes this molecule a prime target for novel therapies. Phospho-tyrosine residue 705 (Tyr705) Stat3 can be used as a potential marker for determining overall survival of node-negative breast cancer patients. Phosphorylated STAT3 might be involved in angiogenesis, anti-apoptosis and tumor progression.

ANTI-PHOSPHO-STAT3 (PTYR705) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-PHOSPHO-STAT3 (PTYR705) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

  • ANTI-ACTIVATED STAT3 (TYR 705)
  • ANTI-STAT3 (PHOSPHORYLATED) (PTYR705)
  • ANTI-STAT3, PHOSPHO-SPECIFIC (TYR705), HUMAN
  • ANTI-STAT3 (PTYR705) MOUSE MAB
  • ANTI-STAT3 (PY705)
  • ANTI-PHOSPHO-STAT3 (PTYR705)
  • ANTI-PHOSPHO-STAT3 (Y705)
  • Anti-APRF antibody produced in rabbit
  • Anti-FLJ20882 antibody produced in rabbit
  • Anti-HIES antibody produced in rabbit
  • Anti-MGC16063 antibody produced in rabbit
  • Anti-signal transducer and activator of transcription 3 (acute-phase response factor) antibody produced in rabbit
  • Anti-STAT3 (Ab-727) antibody produced in rabbit
  • Anti-phospho-STAT3 (pTyr705) antibody produced in rabbit
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