TAK-960

1137868-52-0

CAS-Nr.: 1137868-52-0

Englisch Name:: TAK-960

Synonyma:: CS-554;TAK-960;CS-1725;TAK 960;TAK960;Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,inhibit,phosphorylation,lines,TAK-960;4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide;4-((9-Cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide;Benzamide, 4-[(9-cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)-

CBNumber:: CB62628442

Summenformel:: C27H34F3N7O3

Molgewicht:: 561.6

MOL-Datei:: 1137868-52-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 71

TAK-960 Eigenschaften

Dichte: 1.39±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: ≥28.05 mg/mL in DMSO; insoluble in H2O; ≥12.3 mg/mL in EtOH

Aggregatzustand: solid

pka: 13.21±0.20(Predicted)

Sicherheit

TAK-960 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

TAK-960 is a potent and selective inhibitor of polo-like kinase 1 (PLK1), a serine/threonine protein kinase involved in key processes during mitosis. TAK-960 has shown activity in several tumor cell l ines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 treatments has shown significant efficacy against multiple tumor xenografts and is a potential chemotherapeutic agent f or patients with advanced tumors.

TAK-960 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Benzamide, 4-amino-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)- 2-CHLORO-9-CYCLOPENTYL-7,7-DIFLUORO-5-METHYL-8,9-DIHYDRO-5H-PYRIMIDO[4,5-B][1,4]DIAZEPIN-6(7H)-ONE 1-Methylpiperidin-4-amine 2-Fluoro-5-methoxy-4-nitrobenzoic acid ethyl3-(cyclopentylamino)-2,2-difluoropropanoate 2-chloro-9-cyclopentyl-7,7-difluoro-5,8-dihydropyrimido[4,5-b][1,4]diazepin-6-one Benzoic acid, 2,5-difluoro-4-nitro-, Methyl ester Cyclopentylamin

Downstream Produkte

TAK-960 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 71)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	sales@aceschem.com	United States	19639	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76

TAK-960
4-((9-Cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide
4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide
CS-1725
TAK 960;TAK960
CS-554
Benzamide, 4-[(9-cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)-
Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,inhibit,phosphorylation,lines,TAK-960
1137868-52-0
C27H34F3N7O3