Terpendole E

167427-23-8

CAS-Nr.: 167427-23-8

Englisch Name:: Terpendole E

Synonyma:: FO 2546L;Terpendole E;Terpendole E >=95% (HPLC);1-Benzopyrano[5',6':6,7]indeno[1,2-b]isobenzofuro[5,6-e]indole-2-methanol, 3,4,4a,4b,5,6,6a,7,12,12b,12c,13,14,14a-tetradecahydro-4-hydroxy-α,α,4a,12b,12c-pentamethyl-, (2S,4R,4aR,4bR,6aS,12bS,12cS,14aS)-

CBNumber:: CB62650814

Summenformel:: C28H39NO3

Molgewicht:: 437.61

MOL-Datei:: 167427-23-8.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 22

Terpendole E Eigenschaften

Siedepunkt:: 597.1±50.0 °C(Predicted)

Dichte: 1.194±0.06 g/cm3(Predicted)

storage temp.: -20°C

pka: 14.45±0.70(Predicted)

Aggregatzustand: powder

Farbe: white to beige

Sicherheit

WGK Germany	3

Terpendole E Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Acyl-coenzyme A:cholesterol acyltransferase (ACAT) isozymes are involved with cellular cholesterol esterification and regulate intestinal cholesterol absorption and hepatic lipoprotein secretion. Terpendole E is a related compound of Terpendole C (T116600), which is an inhibitor of ACAT1 and ACAT2 isozymes.

Biochem/physiol Actions

Terpendole E is a mitotic kinesin Eg5 (Kinesin-5) inhibitor isolated from Albophoma yamanashiensis that inhibits both motor and microtubule stimulated ATPase activities of human Eg5. Studies indicate that Terpendole E inhibits Eg5 mutants resistant to S-trityl-L-cysteine and other Eg5 inhibitors. Also, Terpendole E is an ACAT (Acyl-CoA:cholesterol acyltransferase) inhibitor.

Terpendole E Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Terpendole E Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 22)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3989	66
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58
Shanghai Maclean Biochemical Technology Co., LTD	021-50706066 15221275939	shenlinxing@macklin.cn	China	29803	58

Terpendole E
FO 2546L
1-Benzopyrano[5',6':6,7]indeno[1,2-b]isobenzofuro[5,6-e]indole-2-methanol, 3,4,4a,4b,5,6,6a,7,12,12b,12c,13,14,14a-tetradecahydro-4-hydroxy-α,α,4a,12b,12c-pentamethyl-, (2S,4R,4aR,4bR,6aS,12bS,12cS,14aS)-
Terpendole E >=95% (HPLC)
167427-23-8