Terpendole E
- CAS No.
- 167427-23-8
- Chemical Name:
- Terpendole E
- Synonyms
- FO 2546L;Terpendole E;Terpendole E >=95% (HPLC);1-Benzopyrano[5',6':6,7]indeno[1,2-b]isobenzofuro[5,6-e]indole-2-methanol, 3,4,4a,4b,5,6,6a,7,12,12b,12c,13,14,14a-tetradecahydro-4-hydroxy-α,α,4a,12b,12c-pentamethyl-, (2S,4R,4aR,4bR,6aS,12bS,12cS,14aS)-
- CBNumber:
- CB62650814
- Molecular Formula:
- C28H39NO3
- Molecular Weight:
- 437.61
- MDL Number:
- MFCD28346948
- MOL File:
- 167427-23-8.mol
- MSDS File:
- SDS
Terpendole E price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1127 | Terpendole E ≥95% (HPLC) | 167427-23-8 | 250μG | $85.8 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML1127 | Terpendole E ≥95% (HPLC) | 167427-23-8 | 1MG | $286 | 2022-05-15 | Buy |
| Usbiological | 045329 | Terpendole E | 167427-23-8 | 250ug | $312 | 2021-12-16 | Buy |
| TRC | T116620 | TerpendoleE | 167427-23-8 | 1mg | $1350 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0127-C250 | TerpendoleE ≥95%(HPLC) | 167427-23-8 | 250μg | $75 | 2021-12-16 | Buy |
Terpendole E Chemical Properties,Uses,Production
Uses
Acyl-coenzyme A:cholesterol acyltransferase (ACAT) isozymes are involved with cellular cholesterol esterification and regulate intestinal cholesterol absorption and hepatic lipoprotein secretion. Terpendole E is a related compound of Terpendole C (T116600), which is an inhibitor of ACAT1 and ACAT2 isozymes.
Definition
ChEBI: Terpendole E is an organic heterotricyclic compound and an organooxygen compound.
Biochem/physiol Actions
Terpendole E is a mitotic kinesin Eg5 (Kinesin-5) inhibitor isolated from Albophoma yamanashiensis that inhibits both motor and microtubule stimulated ATPase activities of human Eg5. Studies indicate that Terpendole E inhibits Eg5 mutants resistant to S-trityl-L-cysteine and other Eg5 inhibitors. Also, Terpendole E is an ACAT (Acyl-CoA:cholesterol acyltransferase) inhibitor.
Terpendole E Preparation Products And Raw materials
Raw materials
Preparation Products
Terpendole E Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29803 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 66 |
| Sigma-Aldrich | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 58 |
| Energy Chemical | 58 |
| Shanghai Maclean Biochemical Technology Co., LTD | 58 |