ANTI-GLUTAMATE DECARBOXYLASE, G65

CAS-Nr.

Englisch Name:: ANTI-GLUTAMATE DECARBOXYLASE, G65

Synonyma:: Anti-GAD2;ANTI-GAD 65;Anti-MGC161605;Anti-MGC161607;ANTI-GAD 65, 5-22;ANTI-GAD 65, 514-530;Anti-Glutamate decarboxylase 2;ANTI-GLUTAMATE DECARBOXYLASE, 65;ANTI-GLUTAMATE DECARBOXYLASE, G65;ANTI-GLUTAMIC ACID DECARBOXYLASE 65

CBNumber:: CB6406646

Summenformel:

Molgewicht:: 0

MOL-Datei:: Mol file

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 18

ANTI-GLUTAMATE DECARBOXYLASE, G65 Eigenschaften

storage temp.: -20°C

Aggregatzustand: buffered aqueous solution

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

WGK Germany	3

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H315	Verursacht Hautreizungen.	Hautreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P302+P352, P321,P332+P313, P362
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P

Sicherheit

P305+P351+P338

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

ANTI-GLUTAMATE DECARBOXYLASE, G65 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-Glutamic Acid Decarboxylase 65 antibody produced in rabbit is suitable as a primary antibody for the determination of expression of GAD 65 isoform in putative P boutons in rat and mouse at a working dilution of 1:5000 and in lysates prepared from rat testis at different developmental ages and rat cerebellum by immunoblotting.
It is also suitable for immunohistochemistry at a working dilution of 1:500 using formalin-fixed, paraffin-embedded sections of rat pancreas and for microarray.

Allgemeine Beschreibung

GAD is predominantly expressed in the central nervous system (CNS) and pancreatic islets. It is also expressed in testis, oviduct and ovary. GAD exists in two isofoms, GAD 65 and GAD 67. GAD65 is targeted to membranes and nerve endings.

Biochem/physiol Actions

Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L-glutamate to γ-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. It has been identified as an autoantigen in insulin-dependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS) and may serve as a marker in the early stages of IDDM. GAD 65 synthesizes transmitter GABA for vesicular release.

ANTI-GLUTAMATE DECARBOXYLASE, G65 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-GLUTAMATE DECARBOXYLASE, G65 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 18)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

ANTI-GLUTAMATE DECARBOXYLASE, 65
ANTI-GLUTAMATE DECARBOXYLASE B10351, G65
ANTI-GLUTAMATE DECARBOXYLASE, G65
ANTI-GLUTAMATE DECARBOXYLASE (GAD65)
ANTI-GLUTAMIC ACID DECARBOXYLASE 65
ANTI-GLUTAMIC ACID DECARBOXYLASE 65 (GAD65)
ANTI-GAD 65
ANTI-GAD 65, 514-530
ANTI-GAD 65, 5-22
Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse
Anti-Glutamic Acid Decarboxylase 65 (514-530) antibody produced in rabbit
Anti-GAD2/GAD65 antibody produced in goat
Anti-Glutamate decarboxylase 2
Anti-GAD2 antibody produced in rabbit
Anti-Glutamate decarboxylase 2 (pancreatic islets and brain, 65kda)
Anti-GAD2
Anti-glutamate decarboxylase 65 kDa isoform
Monoclonal Anti-GAD65 antibody produced in mouse
Anti-MGC161605
Anti-MGC161607
Anti-Glutamic Acid Decarboxylase 65 (5-22) antibody produced in rabbit