ANTI-OPSIN

ANTI-OPSIN Struktur
CAS-Nr.
Englisch Name:
ANTI-OPSIN
Synonyma:
ANTI-OPSIN;ANTI-RHODOPSIN;ANTI-RHODOPSIN (OPSIN);MONOCLONAL ANTI-RHODOPSIN;Anti-Rhodopsin antibody produced in rabbit;Monoclonal Anti-Opsin antibody produced in mouse;Monoclonal Anti-Rhodopsin antibody produced in mouse
CBNumber:
CB7178388
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-OPSIN Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous solution

Sicherheit

Kennzeichnung gefährlicher Xn
R-Sätze: 21/22
S-Sätze: 36/37
WGK Germany  3

ANTI-OPSIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Mouse monoclonal clone RET-P1 anti-Opsin antibody is used to tag opsin/rhodopsin for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunocytochemistry of cultured cells, immunohistochemistry (paraformaldehyde/glutaraldehyde-fixed, paraformaldehyde perfusion-fixed, frozen sections), immunoelectron microscopy, ELISA, competitive ELISA, and solid phase RIA. It is used as a probe to determine the presence and roles of opsin/rhodopsin in studies of rhodopsin location, functional properties and molecular mechanisms governing rod photoreceptor differentiation.

Allgemeine Beschreibung

Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process of converting light to an electrochemical signal begins when the membrane-bound protein, rhodopsin, absorbs light within the retina. Photoexcitation of rhodopsin causes the cytoplasmic surface of the protein to become catalytically active. In the active state, rhodopsin activates transducin, a GTP binding protein. Once activated, transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE). The decrease of intracellular cGMP concentrations causes the ion channels within the outer segment of the rod or cone to close, thus causing membrane hyperpolarization and, eventually, signal transmission. Rhodopsin′s activity is believed to be shut off by its phosphorylation followed by binding of the soluble protein arrestin.

Biochem/physiol Actions

Mutations in rhodopsin gene are linked to retinitis pigmentosa (RP) and congenital night blindness.

ANTI-OPSIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-OPSIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 11)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
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  • ANTI-RHODOPSIN (OPSIN)
  • ANTI-RHODOPSIN
  • ANTI-OPSIN
  • MONOCLONAL ANTI-RHODOPSIN
  • Monoclonal Anti-Opsin antibody produced in mouse
  • Monoclonal Anti-Rhodopsin antibody produced in mouse
  • Anti-Rhodopsin antibody produced in rabbit
  • OAntibodies
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  • Antibodies to Neural ProteinsAntibodies
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  • RAntibodies
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