ANTI-OPSIN
- CAS No.
- Chemical Name:
- ANTI-OPSIN
- Synonyms
- ANTI-OPSIN;ANTI-RHODOPSIN;ANTI-RHODOPSIN (OPSIN);MONOCLONAL ANTI-RHODOPSIN;Anti-Rhodopsin antibody produced in rabbit;Monoclonal Anti-Opsin antibody produced in mouse;Monoclonal Anti-Rhodopsin antibody produced in mouse
- CBNumber:
- CB7178388
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01865244
- MOL File:
- Mol file
ANTI-OPSIN price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4502636 | Anti-Rhodopsin antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | R9153 | Anti-Rhodopsin antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 50μl | $760 | 2024-03-01 | Buy | |
| Sigma-Aldrich | R5403 | Monoclonal Anti-Rhodopsin antibody produced in mouse clone 1D4, purified immunoglobulin, buffered aqueous solution | 100μL | $630 | 2024-03-01 | Buy | |
| Sigma-Aldrich | O4886 | Monoclonal Anti-Opsin antibody produced in mouse clone RET-P1, ascites fluid | 100μL | $485 | 2024-03-01 | Buy | |
| Sigma-Aldrich | O4886 | Monoclonal Anti-Opsin antibody produced in mouse clone RET-P1, ascites fluid | 0.2mL | $627 | 2024-03-01 | Buy |
ANTI-OPSIN Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Uses
Mouse monoclonal clone RET-P1 anti-Opsin antibody is used to tag opsin/rhodopsin for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunocytochemistry of cultured cells, immunohistochemistry (paraformaldehyde/glutaraldehyde-fixed, paraformaldehyde perfusion-fixed, frozen sections), immunoelectron microscopy, ELISA, competitive ELISA, and solid phase RIA. It is used as a probe to determine the presence and roles of opsin/rhodopsin in studies of rhodopsin location, functional properties and molecular mechanisms governing rod photoreceptor differentiation.
General Description
Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process of converting light to an electrochemical signal begins when the membrane-bound protein, rhodopsin, absorbs light within the retina. Photoexcitation of rhodopsin causes the cytoplasmic surface of the protein to become catalytically active. In the active state, rhodopsin activates transducin, a GTP binding protein. Once activated, transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE). The decrease of intracellular cGMP concentrations causes the ion channels within the outer segment of the rod or cone to close, thus causing membrane hyperpolarization and, eventually, signal transmission. Rhodopsin′s activity is believed to be shut off by its phosphorylation followed by binding of the soluble protein arrestin.
Biochem/physiol Actions
Mutations in rhodopsin gene are linked to retinitis pigmentosa (RP) and congenital night blindness.
ANTI-OPSIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-OPSIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |