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(S)-3-(Hexadecyloxy)propan-1,2-diol

1-O-HEXADECYL-SN-GLYCEROL Struktur
506-03-6
CAS-Nr.
506-03-6
Bezeichnung:
(S)-3-(Hexadecyloxy)propan-1,2-diol
Englisch Name:
1-O-HEXADECYL-SN-GLYCEROL
Synonyma:
CHIMYL ALCOHOL;1-C16 Ether MG;1-hexadecylglycerol;1-o-hexadecylglycerol;MONOCERYL GLYCERYL ETHER;α-hexadecylglyceryl ether;1-O-HEXADECYL-SN-GLYCEROL;1-O-PALMITOYL-SN-GLYCEROL;3-cetyloxypropane-1,2-diol;3-hexadecoxypropane-1,2-diol
CBNumber:
CB7247866
Summenformel:
C19H40O3
Molgewicht:
316.52
MOL-Datei:
506-03-6.mol
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(S)-3-(Hexadecyloxy)propan-1,2-diol Eigenschaften

Schmelzpunkt:
64°
alpha 
D20 +3.0° (c = 1.16 in chloroform)
Siedepunkt:
bp0.005 120°
Dichte
1.0054 (rough estimate)
Brechungsindex
1.4410 (estimate)
storage temp. 
-15°C
Löslichkeit
DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml
Aggregatzustand
A crystalline solid
pka
13.68±0.20(Predicted)
LogP
6.702 (est)

Sicherheit

(S)-3-(Hexadecyloxy)propan-1,2-diol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.

Verwenden

1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing.

Definition

ChEBI: A 1-n-hexadecyl analogue of an optically active alkylglycerol compound.

läuterung methode

Recrystallise it from hexane. [Beilstein 1 III 2322.]

(S)-3-(Hexadecyloxy)propan-1,2-diol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(S)-3-(Hexadecyloxy)propan-1,2-diol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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506-03-6((S)-3-(Hexadecyloxy)propan-1,2-diol)Verwandte Suche:

Glycerintripalmitat (R)-1-[[[(2-Aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethan-1,2-diyldihexadecanoat Batilol 6-O-Palmitoylascorbinsure 2-Aminoethyl-(R)-2,3-bis(hexadecyloxy)propylhydrogenphosphat (R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid Sorbitanstearat beta-D-Galactopyranosid, (3 beta,5 alpha, 22 beta, 25S)-spirosolan-3-yl-O-beta-D-glucopyranosyl-(1=> 2)-O-(beta-D-xylopyranosyl-(1=> 3))-O-beta-D-glucopyranosyl-(1=> 4)- (3β,16α)-3-(β-D-Glucopyranosyloxy)-16-hydroxyolean-12-en-28-sure Octadecansure, Ester mit 1,2,3-Propantriol (R)-1-[[[(2-Aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyloleat Propan-1,2,3-triyltriicosanoat Glycerintristearat Solasonin 2-Hydroxypropan-1,3-diyldipalmitat (R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium-4-oxid O-6-Desoxy-α-L-mannopyranosyl-(1-4)-O-β-D-glucopyranosyl-(1-6)-β-D-glucopyranosyl-(2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oat 3-(6-Desoxy-alpha-L-mannopyranosy-loxy)-1,5,11a,14,19-pentahydroxy-card-20(22)-enolid
  • CHIMYL ALCOHOL
  • 1,2-Propanediol, 3-(hexadecyloxy)-, (2S)-
  • α-hexadecylglyceryl ether
  • 1-hexadecylglycerol
  • 1-o-hexadecylglycerol
  • 3-(hexadecyloxy)-2-propanediol
  • 1-O-PALMITOYL-SN-GLYCEROL
  • 1-O-HEXADECYL-SN-GLYCEROL
  • MONOCERYL GLYCERYL ETHER
  • (S)-3-(hexadecyloxy)propane-1,2-diol
  • (S)-3-(Hexadecyloxy)-1,2-propanediol
  • 3-cetyloxypropane-1,2-diol
  • 3-hexadecoxypropane-1,2-diol
  • 1-O-hexadecyl-sn-glycerol (HG)
  • 1-O-hexadecyl-sn-glycerol (HG)
  • 1-C16 Ether MG
  • 1-O-HEXADECYL-SN-GLYCEROL (HG);1-C16 ETHER MG
  • [S,(+)]-3-O-Hexadecyl-D-glycerol
  • 506-03-6
  • CH3CH215OCH2CHOHCH2OH
  • C19H410O3
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