CDDO-TFEA

932730-52-4

CAS-Nr.: 932730-52-4

Englisch Name:: CDDO-TFEA

Synonyma:: CDDO-TFE;CDDO-TFEA;CDDO-TFEA Exclusive;2-cyano-3,12-dioxo-N-(2,2,2-trifluoroethyl)-oleana-1,9(11)-dien-28-amide;Oleana-1,9(11)-dien-28-amide, 2-cyano-3,12-dioxo-N-(2,2,2-trifluoroethyl)-;(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-N-(2,2,2-trifluoroethyl)-1,3,4,5,6,7,8,8a,14a,14b-decahydropicene-4a-carboxamide

CBNumber:: CB73901916

Summenformel:: C33H43F3N2O3

Molgewicht:: 572.7

MOL-Datei:: 932730-52-4.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 29

CDDO-TFEA Eigenschaften

Siedepunkt:: 661.5±55.0 °C(Predicted)

Dichte: 1.21±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: ≤5mg/ml in ethanol;5mg/ml in DMSO;5mg/ml in dimethyl formamide

Aggregatzustand: crystalline solid

pka: 13.70±0.70(Predicted)

Farbe: White to off-white

Sicherheit

CDDO-TFEA Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The synthetic oleanane triterpenoid CDDO is a Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. CDDO-TFEA is a trifluoroethylamide derivative of CDDO with enhanced ability to cross the blood brain barrier. It has been shown to enhance Nrf2 expression and signaling in various models of neurodegeneration, including those that simulate multiple sclerosis, amyotrophic lateral sclerosis, and Huntington’s disease. CDDO-TFEA induces apoptosis of Ewing’s sarcoma and neuroblastoma cell lines, preventing colony formation at IC₅₀ values ranging from 85-170 nM.

CDDO-TFEA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CDDO-TFEA Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 29)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3506	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Chunchuang (Wuhan) Technology Co., Ltd	15727060112	yutianchun2007@126.com	China	9814	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7982	58
Suzhou Haiben Pharmaceutical Co., Ltd	19353112242	1816280386@qq.com	China	8045	58
Cayman Chemical Company	800-364-9897	sales@caymanchem.com	China	6838	58
Biosynth Biological Technology (Suzhou) Co Ltd	51288865780	sales@biosynth.com	China	6051	58
ApexBio Technology	--	sales@apexbt.com	United States	6251	58

(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-N-(2,2,2-trifluoroethyl)-1,3,4,5,6,7,8,8a,14a,14b-decahydropicene-4a-carboxamide
CDDO-TFE
CDDO-TFEA Exclusive
CDDO-TFEA
Oleana-1,9(11)-dien-28-amide, 2-cyano-3,12-dioxo-N-(2,2,2-trifluoroethyl)-
2-cyano-3,12-dioxo-N-(2,2,2-trifluoroethyl)-oleana-1,9(11)-dien-28-amide
932730-52-4
C33H43F3N2O3