mTOR Activator, MHY1485 - Calbiochem

mTOR Activator, MHY1485 - Calbiochem Struktur
CAS-Nr.
Englisch Name:
mTOR Activator, MHY1485 - Calbiochem
Synonyma:
mTOR Activator, MHY1485 - Calbiochem
CBNumber:
CB74817634
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

mTOR Activator, MHY1485 - Calbiochem Eigenschaften

Sicherheit

mTOR Activator, MHY1485 - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable triazine derivative that is shown to increase cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation level in rat liver Ac2F cells (1 to 2 μM for 1 h), affecting culture viability only at much higher concentrations (by 20% after 24 h 20 μM treatment). MHY1485 induced cellular LC3-II accumulation in Ac2F is reported to be a result of autophagy inhibition due to reduced fusion between autophagosomes and lysosomes. The mechanism of mTOR activation by MHY1485 is currently unknown.

Biochem/physiol Actions

Cell permeable: yes

mTOR Activator, MHY1485 - Calbiochem Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


mTOR Activator, MHY1485 - Calbiochem Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 1)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

  • mTOR Activator, MHY1485 - Calbiochem
Copyright 2019 © ChemicalBook. All rights reserved