mTOR Activator, MHY1485 - Calbiochem
- CAS No.
- Chemical Name:
- mTOR Activator, MHY1485 - Calbiochem
- Synonyms
- mTOR Activator, MHY1485 - Calbiochem
- CBNumber:
- CB74817634
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
mTOR Activator, MHY1485 - Calbiochem price More Price(1)
mTOR Activator, MHY1485 - Calbiochem Chemical Properties,Uses,Production
General Description
A cell-permeable triazine derivative that is shown to increase cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation level in rat liver Ac2F cells (1 to 2 μM for 1 h), affecting culture viability only at much higher concentrations (by 20% after 24 h 20 μM treatment). MHY1485 induced cellular LC3-II accumulation in Ac2F is reported to be a result of autophagy inhibition due to reduced fusion between autophagosomes and lysosomes. The mechanism of mTOR activation by MHY1485 is currently unknown.
Biochem/physiol Actions
Cell permeable: yes
mTOR Activator, MHY1485 - Calbiochem Preparation Products And Raw materials
Raw materials
Preparation Products
mTOR Activator, MHY1485 - Calbiochem Suppliers
Global( 1)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |
mTOR Activator, MHY1485 - Calbiochem