mTOR Activator, MHY1485 - Calbiochem

CAS No.
Chemical Name:
mTOR Activator, MHY1485 - Calbiochem
Synonyms
mTOR Activator, MHY1485 - Calbiochem
CBNumber:
CB74817634
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

mTOR Activator, MHY1485 - Calbiochem price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 5.00554 mTOR Activator, MHY1485 - Calbiochem 10mg $196 2024-03-01 Buy
Product number Packaging Price Buy
5.00554 10mg $196 Buy

mTOR Activator, MHY1485 - Calbiochem Chemical Properties,Uses,Production

General Description

A cell-permeable triazine derivative that is shown to increase cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation level in rat liver Ac2F cells (1 to 2 μM for 1 h), affecting culture viability only at much higher concentrations (by 20% after 24 h 20 μM treatment). MHY1485 induced cellular LC3-II accumulation in Ac2F is reported to be a result of autophagy inhibition due to reduced fusion between autophagosomes and lysosomes. The mechanism of mTOR activation by MHY1485 is currently unknown.

Biochem/physiol Actions

Cell permeable: yes

mTOR Activator, MHY1485 - Calbiochem Preparation Products And Raw materials

Raw materials

Preparation Products

mTOR Activator, MHY1485 - Calbiochem Suppliers

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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
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Sigma-Aldrich 80
mTOR Activator, MHY1485 - Calbiochem