MMP-3 INHIBITOR VIII

208663-26-7

CAS-Nr.: 208663-26-7

Englisch Name:: MMP-3 INHIBITOR VIII

Synonyma:: MMP3 inhibitor 2;MMP-3 INHIBITOR VIII;2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide;N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE;Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-

CBNumber:: CB7481925

Summenformel:: C20H26N2O5S

Molgewicht:: 406.5

MOL-Datei:: Mol file

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 14

MMP-3 INHIBITOR VIII Eigenschaften

Dichte: 1.245±0.06 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml

Aggregatzustand: A crystalline solid

pka: 9.13±0.40(Predicted)

Sicherheit

MMP-3 INHIBITOR VIII Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (K_i = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC₅₀ value of 13 nM.

MMP-3 INHIBITOR VIII Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

MMP-3 INHIBITOR VIII Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 14)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Shanghai Haohong Scientific Co., Ltd.	400-400-8210725	malulu@leyan.com	China	40041	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	5141	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58

MMP-3 INHIBITOR VIII
N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE
2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide
Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-
MMP3 inhibitor 2
208663-26-7