ECHINACOSIDE
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- CAS-Nr.
- 82854-37-3
- Englisch Name:
- ECHINACOSIDE
- Synonyma:
- Cistanche tubulosa;Echicoside;Echinacoside, froM Cistanche deserticola Y.C.Ma;β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate];beta-d-e;Echinoside;ECHINACOSIDE;Echinacosidew;
Purpureaside C;Echinacoside (P)
- CBNumber:
- CB7772340
- Summenformel:
- C35H46O20
- Molgewicht:
- 786.73
- MOL-Datei:
- 82854-37-3.mol
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ECHINACOSIDE Eigenschaften
- Siedepunkt:
- 1062.7±65.0 °C(Predicted)
- Dichte
- 1.66±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- DMSO:60.0(Max Conc. mg/mL);76.26(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.13(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);38.13(Max Conc. mM)
Ethanol:52.5(Max Conc. mg/mL);66.73(Max Conc. mM)
Water:24.36(Max Conc. mg/mL);30.96(Max Conc. mM)
- Aggregatzustand
- powder
- pka
- 8.43±0.20(Predicted)
- Farbe
- White-beige
- BRN
- 4778612
- Stabilität:
- Hygroscopic
- InChIKey
- FSBUXLDOLNLABB-ISAKITKMSA-N
- LogP
- 0.140 (est)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| S-Sätze: |
24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
LZ5786500 |
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| HS Code |
29389090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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ECHINACOSIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Echinacoside is a phenylethanoid glycoside that has been found in
Echinacea and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals (EC
50 = 6.6 μM in a cell-free assay). Echinacoside (10 μg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells. It reduces increases in plasma alanine aminotransferase (ALT), TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury when administered at a dose of 60 mg/kg. Echinacoside (20 mg/kg per day for 15 days) prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in a mouse model of MPTP-induced Parkinson''s disease. It also improves motor performance in the rotarod test in the same model.
Chemische Eigenschaften
White powder
Verwenden
Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.
ECHINACOSIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ECHINACOSIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 267)Lieferanten
82854-37-3()Verwandte Suche:
- (1-3)-o-(beta-d-glucopyranosyl-(1-6))-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat
- 2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid
- beta-d-e
- ECHINACOSIDE
- ECHINACOSIDE(AMERICAN HERBAL PHARMACOPOEIA)
- ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E.
- Echinacoside/CH80711
- Echinacoside/CH54339
- ECHINACOSIDE(AHP)
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Purpureaside C
- ECHINACOSIDE WITH HPLC
- 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-β-D-glucopyranosyl-4-O-[3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside
- [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
- Echinacoside
[(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)
- Echinacoside, 98%, from Cistanche deserticola Y.C.Ma
- Echinacoside Standard
- (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl 3-(3,4-dihydroxyphenyl)acrylate
- (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl 3-(3,4-
- Cistanche tubulosa extrac
- Echinacoside, froM Cistanche deserticola Y.C.Ma
- Cistanche tubulosa
- Echicoside
- β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
- Cistanche Deserticola Extract Echinacoside
- Echinacosidew
- Echinacoside (P)
- Echinacea Purpurea Cichoric Acid
- Echinoside
- 82854-37-3
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Sugars, Carbohydrates & Glucosides
