D609

D609 Struktur
83373-60-8
CAS-Nr.
83373-60-8
Englisch Name:
D609
Synonyma:
D609;D609 ,98%;D609,D-609;D-609 POTASSIUM;D609 POTASSIUM SALT;D609 potassium salt,98%;Tricyclodecan-9-yl xanthate;Tricyclodecan-9-yl xanthogenate;tricyclodecane-9-yl-xanthogenate;TRICYCLODECAN-9-YL XANTHOGENATE K
CBNumber:
CB9249743
Summenformel:
C11H17KOS2
Molgewicht:
268.47
MOL-Datei:
83373-60-8.mol

D609 Eigenschaften

storage temp. 
0-6°C
Löslichkeit
H2O: 300 mg/mL
Aggregatzustand
solid
Farbe
off-white
Wasserlöslichkeit
Soluble to 100 mM in water
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
R-Sätze: 22
S-Sätze: 24/25
WGK Germany  3
HS Code  29333990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P330 Mund ausspülen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

D609 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

D609 is a xanthate and a competitive inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC; Ki = 6.4 μM). It has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations when used at concentrations of 100 and 200 mg/ml, respectively. Similar to other xanthates, D609 has antioxidant, antiviral, and anti-tumor activities. In addition, it has anti-inflammatory actions, inhibiting LPS-stimulated expression of nitric oxide synthase (NOS) in phagocytes (IC50 = 20 μg/ml) and IL-1β-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in endothelial cells.

Chemische Eigenschaften

white to off-white solid

Verwenden

D609 has been used as a phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor in mouse bone marrow derived monocytes. D609 has also been reported to significantly reduce the elevated levels of phosphatidylethanolamine binding protein 1 (PEBP1) in apolipoprotein E-/- mice.

Biologische Aktivität

Selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (K i = 6.4 μ M); antiviral and antitumor agent. Suppresses LPS- and IFN γ -induced NO production (IC 50 = 20 mg/ml) and blocks oxidative glutamate toxicity in nerve cells. Antioxidant in vivo .

D609 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


D609 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 87)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32480 60
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49390 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Career Henan Chemica Co
+86-0371-86658258 15093356674;
laboratory@coreychem.com China 30255 58
Finetech Industry Limited
+86-27-87465837 +8618971612321
info@finetechnology-ind.com China 9702 58
Labnetwork lnc.
+86-27-50766799 +8618062016861
contact@labnetwork.com China 19994 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131981 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69

83373-60-8()Verwandte Suche:


  • Tricyclodecan-9-yl xanthate
  • Tricyclodecan-9-yl xanthate potassium salt
  • Tricyclodecan-9-yl xanthogenate
  • D609 potassium salt,98%
  • Carbonodithioic acid O-(octahydro-4,7-methano-1H-inden-5-yl) ester potassium salt
  • tricyclodecane-9-yl-xanthogenate
  • D609 ,98%
  • CARBONODITHIOIC ACID, O-(OCTAHYDRO-4,7-METH
  • TRICYCLODECAN-9-YL XANTHOGENATE K
  • TRICYCLODECAN-9-YL XANTHOGENATE POTASSIUM SALT
  • CARBONODITHIOIC ACID, O-(OCTAHYDRO-4,7-METHANO-1H-INDEN-5-YL) ESTER POTASSIUM
  • D609
  • D-609 POTASSIUM
  • D609 POTASSIUM SALT
  • O-TRICYCLO[5.2.1.0(2,6)]DEC-9-YL DITHIOCARBONATE POTASSIUM SALT
  • O-(OCTAHYDRO-4,7-METHANO-1H-INDEN-5-YL) CARBONOPOTASSIUM DITHIOATE
  • potassium O-(octahydro-4,7-methano-1H-inden-5-yl) dithiocarbonate
  • O-TRICYCLO(5.2.1.02,6)DEC-9-YL*DITHIOCAR BONATE POTA
  • Dithiocarbonic acid O-[(octahydro-4,7-methano-1H-inden)-5-yl]S-potassium salt
  • D609, Potassium Salt - CAS 83373-60-8 - Calbiochem
  • O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate
  • D609,O-(Octahydro-4,7-methano-1H-inden-5-yl)carbonopotassiumdithioate
  • potassium O-(octahydro-1H-4,7-methanoinden-5-yl) carbonodithioate
  • D609,D-609
  • 83373-60-8
  • C11H15KOS2
  • Biochemicals and Reagents
  • BioChemical
  • P to Q
  • Phospholipase C, phosphatidylcholine-specific
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Lipid signaling
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