MATRILYSIN

MATRILYSIN Struktur
141256-52-2
CAS-Nr.
141256-52-2
Englisch Name:
MATRILYSIN
Synonyma:
MMP-7;PUMP-1;RHMMP-7;MMP7 HUMAN;MATRILYSIN;HUMAN MMP-7;MATRILYSIN-1;EC 3.4.24.23;RHMMP-7, ACTIVE;Pump-1 protease
CBNumber:
CB9439940
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

MATRILYSIN Eigenschaften

storage temp. 
-70°C
Aggregatzustand
buffered aqueous solution

Sicherheit

Kennzeichnung gefährlicher B
WGK Germany  3
HS Code  3504009000

MATRILYSIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Matrix metalloproteinase-7 (MMP7) human has been used in in silico analysis of MMP-7 proteolysis of perlecan.

Allgemeine Beschreibung

Matrix metalloproteinase-7 (MMP7) also referred to as matrilysin is encoded by the gene mapped to human chromosome 11q21-q22. MMP7 is a smallest member of MMP enzyme family and is highly expressed in cancer cells. MMP7 is exclusively released by epithelial cells.

Biochem/physiol Actions

Matrix metalloproteinase-7 (MMP-7) catalyzes the cleavage of extracellular matrix (ECM) proteins such as proteoglycans, fibronectin, entactin, laminin, collagen III/ IV/ V/ IX/ X/ XI, type I/ II/ IV/ V gelatins, and elastin. Matrix metalloproteinase-7 facilitates initial stages of tumor progression. Activated MMP7 plays a vital role in human colorectal cancer (CRC) liver metastases. Overexpression of MMP7 is observed in various human cancers, such as breast, lung, prostate, esophagus, stomach, endometrium, and ovarian carcinomas, as well as esophageal squamous cell carcinomas. Increased expression of MMP7 is also associated with pathogenesis of demyelinating multiple sclerosis (MS) lesions. Both in silico and in vitro studies show that MMP7 degrades glycosylated and basement membrane bound perlecan and plays a vital role in prostate cancer cell invasion.

MATRILYSIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


MATRILYSIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 24)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Wuhan Chemstan Biotechnology Co., Ltd. 15926423062
422450190@qq.com China 10132 58
Shanghai Yaji Biological Technology Co., Ltd. 021-34661275 15301693058
yajikit@163.com China 6633 58
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749
sales@shzbio.com China 9965 58
AntibodySystem 027-65279366 18162686757
biolab-reagents@atagenix.com China 9790 58
United States Biological --
sales@advtechind.com United States 6106 58

  • Anti-MMP-7, C-Terminal antibody produced in rabbit
  • Pump-1 protease
  • Uterine metalloproteinase
  • PUMP-1
  • PUMP-1, ACTIVE, HUMAN, RECOMBINANT
  • RHMMP-7
  • RHMMP-7, ACTIVE
  • MMP-7
  • MMP-7 ENZYME, HUMAN
  • MMP7 HUMAN
  • MMP-7, HUMAN, RECOMBINANT, E COLI
  • MMP-7, ACTIVE, HUMAN, RECOMBINANT
  • MATRILYSIN
  • MATRILYSIN-1
  • MATRILYSIN, ACTIVE, HUMAN, RECOMBINANT
  • MATRILYSIN HUMAN
  • MATRIX METALLOPROTEINASE-7
  • EC 3.4.24.23
  • HUMAN MMP-7
  • HUMAN MATRIX METALLOPROTEINASE 7
  • Recombinant Human Matrix Metalloproteinase-7
  • Matrilysin-1, MMP-7
  • MATRIX METALLOPROTEINASE-7 HUMAN
  • Matrix Metalloproteinase-7 from human, Recombinant
  • Human MMP7 Protein, Fc Tag
  • 141256-52-2
  • enzyme
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