ChemicalBook >> CAS DataBase List >>N-Methyl-1H-Indole-5-EthaneSulphonamide
N-Methyl-1H-Indole-5-EthaneSulphonamide
- CAS No.
- 98623-50-8
- Chemical Name:
- N-Methyl-1H-Indole-5-EthaneSulphonamide
- Synonyms
- 2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide;ratriptanImpurity5;N-Methyl-1H-Indole-5-EthaneSulphomide;N-Methyl-1H-indole-5-ethanesulfonamide;N-Methyl-1H-Indole-5-EthaneSulphonamide;1H-Indole-5-ethanesulfonamide, N-methyl-;2-(1H-indol-5-yl)-N-MethylethanesulfonaMide;N-Methyl-1H-indole-5-ethanesulfonamide, >=98%;2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide;2-(1H-Indol-5-yl) -ethanesulfonic acid methyl amide
- CBNumber:
- CB01023956
- Molecular Formula:
- C11H14N2O2S
- Molecular Weight:
- 238.31
- MDL Number:
- MOL File:
- 98623-50-8.mol
- MSDS File:
- SDS
Last updated:2025-07-04 14:25:19
| Melting point | 124-125°C |
|---|---|
| Boiling point | 458.4±47.0 °C(Predicted) |
| Density | 1.316±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 11.52±0.40(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C11H14N2O2S/c1-12-16(14,15)7-5-9-2-3-11-10(8-9)4-6-13-11/h2-4,6,8,12-13H,5,7H2,1H3 |
| InChIKey | PPXMUBLAPJLGNE-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(CCS(NC)(=O)=O)C=C2)C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317 |
| Precautionary statements | P280-P305+P351+P338 |
N-Methyl-1H-Indole-5-EthaneSulphonamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M313525 | N-Methyl-1H-indole-5-ethanesulfonamide | 98623-50-8 | 500mg | $180 | 2021-12-16 | Buy |
| TRC | M313525 | N-Methyl-1H-indole-5-ethanesulfonamide | 98623-50-8 | 2.5g | $675 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0294434 | N-METHYL-1H-INDOLE-5-ETHANE SULFONAMIDE 98.00% | 98623-50-8 | 25G | $2106.72 | 2021-12-16 | Buy |
| aablocks | AA005TYY | N-Methyl-1h-indole-5-ethanesulfonamide 97% | 98623-50-8 | 100mg | $95 | 2021-12-16 | Buy |
| AHH | MT-57055 | N-Methyl-1H-indole-5-ethanesulfonamide 98% | 98623-50-8 | 25g | $770 | 2021-12-16 | Buy |
N-Methyl-1H-Indole-5-EthaneSulphonamide Chemical Properties,Uses,Production
Uses
N-Methyl-1H-indole-5-ethanesulfonamide is used as a reagent in the synthesis of Naratriptan Hydrochloride (N378730); a triptan drug used for the treatment of migraine headaches.
General Description
N-Methyl-1H-Indole-5-EthaneSulphonamide, also known as 2-(1H-Indol-5-yl)-N-methylethanesulfonamide, is a white solid.
Synthesis
At 40-45 ℃ (hydrogen pressure: 3-4 kg/cm2), 2-(3-Phenylsulf-anyl-1H-indol-5-yl)-ethanesulfonic acidmethylamide (14) (5 g, 0.014 mol) was hydrogenated in ethanol: water (7:3) (40 ml) in an autoclave for 10 h. After that, the reaction mass was cooled to room temperature, followed by removing the catalyst through filtering. The filtrate was distilled out to get N-Methyl-1H-Indole-5-EthaneSulphonamide. 
Synthesis of N-Methyl-1H-Indole-5-EthaneSulphonamide from 1H-Indole-5-ethanesulfonamide, N-methyl-3-(phenylthio)-
N-Methyl-1H-Indole-5-EthaneSulphonamide Preparation Products And Raw materials
Global( 71)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | shangli@bocchem.com | China | 138 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 | sales@rlavie.com | China | 1030 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Hangzhou Proserre Chemical Co.,Ltd. | +86-571-86088112 | info@proserre.com | China | 1077 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from N-Methyl-1H-Indole-5-EthaneSulphonamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-09-12 | N-Methyl-1H-indole-5-ethanesulphonaMide
98623-50-8
|
US $0.00-0.00 / G | 1G | 98%min | 100kg/month | Shanghai Rlavie Technology Co ltd | |
 |
2020-01-10 | N-Methyl-1H-Indole-5-EthaneSulphonamide
98623-50-8
|
US $1.00 / g | 1g | 97% | 100kg | Career Henan Chemical Co |
-
- N-Methyl-1H-indole-5-ethanesulphonaMide
98623-50-8
- US $0.00-0.00 / G
- 98%min
- Shanghai Rlavie Technology Co ltd
-
- N-Methyl-1H-Indole-5-EthaneSulphonamide
98623-50-8
- US $1.00 / g
- 97%
- Career Henan Chemical Co
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N-Methyl-1H-Indole-5-EthaneSulphonamide
N-Methyl-1H-indole-5-ethanesulfonamide
2-(1H-indol-5-yl)-N-MethylethanesulfonaMide
N-Methyl-1H-indole-5-ethanesulfonamide, >=98%
N-Methyl-1H-Indole-5-EthaneSulphomide
1H-Indole-5-ethanesulfonamide, N-methyl-
2 - (1h-indole-5-yl) - n-methylethyl-1-sulfonamide
2-(1H-indol-5-yl)-N-methylethane-1-sulfonamide
ratriptanImpurity5
N-Methyl-1H-indole-5-ethanesulfonamide (2-(1H-Indol-5-yl)-N-methylethanesulfonamide)
2-(1H-Indol-5-yl) -ethanesulfonic acid methyl amide
98623-50-8