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1-Hydroxyibuprofen

1-Hydroxyibuprofen structure

CAS No.: 53949-53-4

Chemical Name:: 1-Hydroxyibuprofen

Synonyms: 1-Hydroxyibuprofen;Ibuprofen EP Impurity L;Ibuprofen Impurity 12;Ibuprofen EP Impurity;Ibuprofen IMpurity-L(EP/BP);C14278150 Ibuprofen-1-hydroxy;Arginine ibuprofen impurity L;2-[4-(1-Hydroxy-2-methylpropyl)phen;1-Hydroxyibuprofen 100 μg/ml Acetonitrile;1-Hydroxy Ibuprofen (Ibuprofen Impurity L)

CBNumber:: CB01062052

Molecular Formula:: C13H18O3

Molecular Weight:: 222.28

MDL Number:: MFCD08275586

MOL File:: 53949-53-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-21 10:31:43

Product description	Number	Pack Size	Price
IBUPROFEN IMPURITY L pharmaceutical secondary standard, certified reference material	PHR3325	50 mg	$536
1-Hydroxyibuprofen pharmaceutical impurity standard	62248	50mg	$582
1-Hydroxyibuprofen VETRANAL	32496	10mg	$498
1-hydroxy Ibuprofen ≥98%	36295	5mg	$63
1-hydroxy Ibuprofen ≥98%	36295	10mg	$112
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1-Hydroxyibuprofen Properties

Melting point	80-85°C
Boiling point	367.5±22.0 °C(Predicted)
Density	1.119±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Acetonitrile (Slightly), Chloroform (Slightly, Heated), Methanol (Slightly)
pka	4.39±0.10(Predicted)
color	White to Off-White
BRN	22307543
Major Application	forensics and toxicology pharmaceutical (small molecule)
InChI	InChI=1S/C13H18O3/c1-8(2)12(14)11-6-4-10(5-7-11)9(3)13(15)16/h4-9,12,14H,1-3H3,(H,15,16)
InChIKey	RMOQYHYFRKTDRI-UHFFFAOYSA-N
SMILES	C1(C(C)C(O)=O)=CC=C(C(O)C(C)C)C=C1
FDA UNII	8A1S87ZA87
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312+P330

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	0
2		0

1-Hydroxyibuprofen price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR3325	IBUPROFEN IMPURITY L pharmaceutical secondary standard, certified reference material	53949-53-4	50 mg	$536	2026-04-30	Buy
Sigma-Aldrich	62248	1-Hydroxyibuprofen pharmaceutical impurity standard	53949-53-4	50mg	$582	2026-04-30	Buy
Sigma-Aldrich	32496	1-Hydroxyibuprofen VETRANAL	53949-53-4	10mg	$498	2026-04-30	Buy
Cayman Chemical	36295	1-hydroxy Ibuprofen ≥98%	53949-53-4	5mg	$63	2026-04-30	Buy
Cayman Chemical	36295	1-hydroxy Ibuprofen ≥98%	53949-53-4	10mg	$112	2026-04-30	Buy

Product number	Packaging	Price	Buy
PHR3325	50 mg	$536	Buy
62248	50mg	$582	Buy
32496	10mg	$498	Buy
36295	5mg	$63	Buy
36295	10mg	$112	Buy

1-Hydroxyibuprofen Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

1-Hydroxy Ibuprofen, also known as Ibuprofen EP Impurity L, is a degradation product of Ibuprofen. Ibuprofen is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and non-selective COX inhibitor.

Definition

ChEBI: 1-Hydroxyibuprofen is a monocarboxylic acid and a member of benzenes.

1-Hydroxyibuprofen Preparation Products And Raw materials

Raw materials

IBUPROFEN SODIUM SALT rac 2-Hydroxy Ibuprofen rac a-Hydroxy Ibuprofen Ibuprofen

Preparation Products

4'-(2-Methylpropyl)acetophenone

1-Hydroxyibuprofen Suppliers

Global( 117)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30227	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8645	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
Suzhou ARTK Medchem Co., Ltd.	+8618118463618	sales1@artkmedchem.com	China	39021	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.	+undefined18603013401	jack.lin@sincopharmachem.com	China	9996	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
CR Corporation Limited	58
sgtlifesciences pvt ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58
Suzhou ARTK Medchem Co., Ltd.	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.	58

View Lastest Price from 1-Hydroxyibuprofen manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-21	1-Hydroxy-ibuprofen 53949-53-4	US $366.00-816.00 / mg			10g	TargetMol Chemicals Inc.

1-Hydroxy-ibuprofen
53949-53-4
US $366.00-816.00 / mg
TargetMol Chemicals Inc.

53949-53-4(1-Hydroxyibuprofen)Related Search:

6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one Ibuprofen EP Impurity I (R)-(-)-IBUPROFEN rac 2-Hydroxy Ibuprofen 2-(4-Methylphenyl)propanoic acid

2-[4-(2-Methylpropyl)phenyl] ethanol Ibuprofen Ethyl Ester (S)-(+)-Ibuprofen rac a-Hydroxy Ibuprofen trans-Ibuprofen IMpurity G

4-(2-Methylpropyl)benzeneethanol 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE M-ISOBUTYL IBUPROFEN (2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID

3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID 4'-(2-Methylpropyl)acetophenone (2RS)-2-(4-BUTYLPHENYL)PROPANOIC ACID

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1-Hydroxy Ibuprofen (Ibuprofen Impurity L)(Mixture of Diastereomers) 2-[4'-(1-Hydroxy-2-methylpropyl)phenyl]propionic Acid 4-(1-Hydroxy-2-methylpropyl)-a-methylbenzeneacetic Acid Benzeneacetic acid, 4-(1-hydroxy-2-methylpropyl)--alpha--methyl- (9CI) 4-(1-Hydroxy-2-Methylpropyl)-α-Methylbenzeneacetic Acid Ibuprofen IMpurity-L(EP/BP) 1-Hydroxy Ibuprofen (Ibuprofen Impurity L) 1-Hydroxy-ibuprofen - Mixture of diastereoisomers Ibuprofen EP Impurity Imp. L (EP): 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic Acid(1-Hydroxyibuprofen) Ibuprofen Impurity 12 Ibuprofen impurity 6/Ibuprofen EP Impurity L/1-Hydroxy Ibuprofen Ibuprofen EP Impurity L：Ibuprofen Impurity L 2-[4-(1-Hydroxy-2-methylpropyl)phen Benzeneacetic acid, 4-(1-hydroxy-2-methylpropyl)-α-methyl- Ibuprofen Impurity 12（Ibuprofen EP Impurity L） 2-(4-(1-HYDROXY-2-METHYLPROPYL)-PHENYL)-PROPIONSAEURE Ibuprofen EP Impurity L 1-Hydroxyibuprofen 4-(1-hydroxy-2-methylpropyl)-alpha-methyl-Benzeneacetic acid 1-Hydroxyibuprofen 100 μg/ml Acetonitrile C14278150 Ibuprofen-1-hydroxy Arginine ibuprofen impurity L 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic Acid (1-Hydroxyibuprofen) Ibuprofen Impurity L(Mixture of Diastereomers) Ibuprofen Imp. L (EP): 2-4-(1-Hydroxy-2-methylpropyl) phenylpropanoic acid 53949-53-4 PHENYL Aromatics Impurities Intermediates & Fine Chemicals Pharmaceuticals