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(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane structure

CAS No.: 156474-22-5

Chemical Name:: (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

Synonyms: Atazanavir Impurity 32;(2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane;(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane;threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide;tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate;(2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane;tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate;(2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane;tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate;2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate

CBNumber:: CB01122327

Molecular Formula:: C15H21NO3

Molecular Weight:: 263.33

MDL Number:: MFCD08061626

MOL File:: 156474-22-5.mol

Last updated:2023-07-22 08:27:56

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(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Properties

Melting point	90-95°C
Boiling point	398.8±25.0 °C(Predicted)
Density	1.118±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform, DMSO, Methanol
form	Solid
pka	12.19±0.46(Predicted)
color	White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	CHM0068781	(2S,3R)-3-(N-BOC-AMINO)-1-OXIRANE-4-PHENYLBUTANE 95.00%	156474-22-5	5MG	$502.81	2021-12-16	Buy
JR MediChem	JR6-L2705	Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester 96%	156474-22-5	1g	$980	2021-12-16	Buy
JR MediChem	JR6-L2705	Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester 96%	156474-22-5	5g	$2480	2021-12-16	Buy
JR MediChem	JR6-L2705	Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester 96%	156474-22-5	25g	$7980	2021-12-16	Buy
Ambeed	A789622	tert-Butyl((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbamate 97%	156474-22-5	1g	$43	2021-12-16	Buy

Product number	Packaging	Price	Buy
CHM0068781	5MG	$502.81	Buy
JR6-L2705	1g	$980	Buy
JR6-L2705	5g	$2480	Buy
JR6-L2705	25g	$7980	Buy
A789622	1g	$43	Buy

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Chemical Properties,Uses,Production

Uses

(2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir (A790050), a novel azapeptide HIV protease inhibitor used as an antiviral agent.

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane synthesis

Synthesis of (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane from 3R enantiomer

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Suppliers

Global( 57)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Hangzhou Proserre Chemical Co.,Ltd.	+86-571-86088112	info@proserre.com	China	1077	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76

Supplier	Advantage
Standardpharm Co. Ltd.	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
BOC Sciences	58
Nextpeptide Inc	58
Hangzhou Proserre Chemical Co.,Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
China National Standard Pharmaceutical Corporation Limited	58
LEAPCHEM CO., LTD.	58
J & K SCIENTIFIC LTD.	76

156474-22-5((2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane)Related Search:

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane Atazanavir Impurity 6 Des(benzylpyridyl) Atazanavir Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir Trihydrochloride Atazanavir Impurity 8

(3R,8S,9S,12R)-Atazanavir threo-N-(Tert-Butoxy)Carbonyl L-homophenylalanine epoxide (S)-1-(TERT-BUTOXYCARBONYL)-2,3-OXIRANYLMETHYLAMINE 4-(2-Pyridinyl)benzaldehyde (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane

Atazanavir Impurity Atazanavir S,S,R,S-Diastereomer (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane TERT-BUTYL N-(2-OXIRANYLMETHYL)CARBAMATE Atazanavir

tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Atazanavir IMpurity 4 Atazanavir Sulfate

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(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane (2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate 2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide (2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane Atazanavir Impurity 32 tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate (2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane Carbamic acid, N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-, 1,1-dimethylethyl ester Atazanavir Intermediate Enantiomer ((2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane) 156474-22-5 Aromatics, Chiral Reagents, Heterocycles