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ChemicalBook >> CAS DataBase List >>(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide

(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide

(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide Structure
(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide structure
CAS No.
120555-31-9
Chemical Name:
(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide
Synonyms
Ro 24-0238;Ro240238,Ro 24 0238;5-(4-Methoxyphenyl)-N-(1-methyl-4-(3-pyridinyl)butyl)-2,4-decadienamide;(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide;(2E,4E)-5-(4-Methoxyphenyl)-N-[(R)-1-methyl-4-(3-pyridinyl)butyl]-2,4-decadienamide;2,4-Decadienamide, 5-(4-methoxyphenyl)-N-[(1R)-1-methyl-4-(3-pyridinyl)butyl]-, (2E,4E)-
CBNumber:
CB01253726
Molecular Formula:
C27H36N2O2
Molecular Weight:
420.59
MDL Number:
MFCD00884705
MOL File:
120555-31-9.mol
Last updated:2025-04-18 09:51:29
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(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide Properties

Melting point 88-89 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
Boiling point 627.1±55.0 °C(Predicted)
Density 1.026±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 14.07±0.46(Predicted)
FDA UNII 7G3UI0W9Y5

(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide Chemical Properties,Uses,Production

Uses

Ro-24-0238 is an antagonist of platelet activating factor (PAF) and inhibitor of thromboxane synthesis, used for lessening the inflammation and damage resulting from a local release of PAF.

in vivo

Pretreatment with 3 mg/kg Ro 24-0238 and 3 mg/kg WEB 2086 decreases the accumulation of neutrophils within the mucosa in rats[1].

References

[1] Will PC, et al. Platelet activating factor as a proinflammatory mediator in acetic-induced colitis in the rat. Agents Actions. 1991 Sep;34(1-2):181-4. DOI:10.1007/BF01993272

(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide Preparation Products And Raw materials

Raw materials

Preparation Products

(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32281 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19903 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29772 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24890 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 6051 58
Adooq Bioscience LLC 400-025-6535 sales@adooq.cn China 6215 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
MedChemexpress LLC 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Biosynth Biological Technology (Suzhou) Co Ltd 58
Adooq Bioscience LLC 58

View Lastest Price from (2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ro-24-0238 pictures 2024-10-24 Ro-24-0238
120555-31-9
 US $1970.00-3400.00 / mg 10g TargetMol Chemicals Inc.
  • Ro-24-0238 pictures
  • Ro-24-0238
    120555-31-9
  • US $1970.00-3400.00 / mg
  • TargetMol Chemicals Inc.
(2E,4E)-5-(4-methoxyphenyl)-N-[(2R)-5-pyridin-3-ylpentan-2-yl]deca-2,4 -dienamide Ro 24-0238 (2E,4E)-5-(4-Methoxyphenyl)-N-[(R)-1-methyl-4-(3-pyridinyl)butyl]-2,4-decadienamide 2,4-Decadienamide, 5-(4-methoxyphenyl)-N-[(1R)-1-methyl-4-(3-pyridinyl)butyl]-, (2E,4E)- Ro240238,Ro 24 0238 5-(4-Methoxyphenyl)-N-(1-methyl-4-(3-pyridinyl)butyl)-2,4-decadienamide 120555-31-9 C27H36N2O2