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Lithium dodecyl sulfate

CAS No.
2044-56-6
Chemical Name:
Lithium dodecyl sulfate
Synonyms
LDS;hMAD;LITHIUM LAURYL SULPHATE;LiDS;JV15;hSMAD;hMAD-3;hSMAD3;MAD homolog;Press-on Lids
CBNumber:
CB0150488
Molecular Formula:
C12H25LiO4S
Molecular Weight:
272.33
MDL Number:
MFCD00007467
MOL File:
2044-56-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:21:29

Lithium dodecyl sulfate Properties

Melting point 100-123 °C
Boiling point 199℃[at 101 325 Pa]
Density 1.168[at 20℃]
vapor pressure 6.5Pa at 20℃
storage temp. Inert atmosphere,Room Temperature
solubility H2O: 0.1 M at 20 °C, clear, colorless
form Shiny Crystalline Flakes or Powder
color White
PH pH(0.25mol/l, 25℃) : 5.0~10.5
Appearance White to Almost white powder to crystal.
Water Solubility Soluble in water.
BRN 5186718
Stability Stable. Incompatible with strong oxidizing agents.
InChI InChI=1S/C12H26O4S.Li/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
InChIKey YFVGRULMIQXYNE-UHFFFAOYSA-M
SMILES C(COS([O-])(=O)=O)CCCCCCCCCC.[Li+]
CAS DataBase Reference 2044-56-6(CAS DataBase Reference)
EPA Substance Registry System Sulfuric acid, monododecyl ester, lithium salt (2044-56-6)
Absorption ≤0.05 at 260nm (3% solution)
≤0.05 at 280nm (3% solution)
UNSPSC Code 47121804
NACRES NB.43

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)Exclamation Mark (GHS07)
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H228-H315-H318-H335
Precautionary statements  P210-P280-P302+P352-P305+P351+P338+P310
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,C,F
Risk Statements  36/37/38-34-20/21/22-15-14-11-41-37/38
Safety Statements  26-36-45-43-36/37/39-16-7/8-3/7/9-39
RIDADR  UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., HI: all
WGK Germany  3
F  3
TSCA  TSCA listed
HazardClass  4.1
HS Code  29209010
Storage Class 4.1B - Flammable solid hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 3
Eye Dam. 1
Flam. Sol. 1
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
NFPA 704
1
2 0

Lithium dodecyl sulfate price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L4632 Lithium dodecyl sulfate ≥98.5% (GC) 2044-56-6 5g $68.7 2026-04-30 Buy
Sigma-Aldrich L4632 Lithium dodecyl sulfate ≥98.5% (GC) 2044-56-6 25g $198 2026-04-30 Buy
Sigma-Aldrich BR65643 BRAND® desiccator ′Novus′ lid with knob nominal diameter × O.D. × H 250 mm × 320 mm × 115 mm, with knob lid 1 ea $173 2025-07-31 Buy
Sigma-Aldrich BR71776 BRAND® push-on lid for buckets for 10L buckets 1 ea $12.5 2025-07-31 Buy
Sigma-Aldrich BR65631 BRAND® desiccator ′Novus′ lid with knob nominal diameter × O.D. × H 150 mm × 215 mm × 78 mm, with knob lid 1 ea $155 2025-07-31 Buy
Product number Packaging Price Buy
L4632 5g $68.7 Buy
L4632 25g $198 Buy
BR65643 1 ea $173 Buy
BR71776 1 ea $12.5 Buy
BR65631 1 ea $155 Buy

Lithium dodecyl sulfate Chemical Properties, Uses, Production

Description

Lithium dodecyl sulfate (LDS) is an anionic detergent and surfactant that is frequently used in electrophoresis and chromatography. LDS may be substituted for sodium dodecyl sulfate (SDS) in electrophoresis under cold conditions. The use of LDS in micellar electrokinetic chromatography has been extensively studied. A report has been published on the partition equilibria of LDS between water and bilayer membranes. LDS has been utilized in protein electrophoresis and proteomics studies. The three-dimensional structure of the amyloid β-protein fragment 25-35 has been investigated in LDS micelles by two-dimensional 1HNMR. LDS has been used to induce changes in protein conformation.

Chemical Properties

Lithium dodecyl sulfate is a white, shiny crystalline powder or flake, soluble in organic solvents such as alcohols, ethers, and hydrocarbons, but only slightly soluble in water. It exhibits good thermal stability and remains stable at room temperature. As an anionic surfactant, it demonstrates excellent surface activity.

Uses

Anionic detergent that may be used in place of SDS for electrophoresis in cold conditions.

Uses

Lithium dodecyl sulfate has been used as a component of lysis buffer.

Flammability and Explosibility

Flammable

Purification Methods

Recrystallise this detergent twice from absolute EtOH and dry it under vacuum. Critical Micellar Concentration (CMC) in H2O is 8.77 x 10-3M. [Mukerjee et al. J Phys Chem 71 4166 1967, Mysels & Dulin J Colloid Sci 10 461 1955, Beilstein 1 IV 1847.]

Precautions

In general, autoclaved lauryl sulfate solutions undergo hydrolysis to yield lauryl alcohol, which precipitates from solution, and sulfuric acid, which decreases the solution pH. It is not advised to autoclave lauryl sulfate solutions.

References

[1] ELISABET FUGUET. Solute−Solvent Interactions in Micellar Electrokinetic Chromatography. 6. Optimization of the Selectivity of Lithium Dodecyl Sulfate−Lithium Perfluorooctanesulfonate Mixed Micellar Buffers[J]. Analytical Chemistry, 2002, 74 17: 4447-4455. DOI:10.1021/ac0201530.
[2] M D TRONE. Characterization of chemical selectivity in micellar electrokinetic chromatography. VI. Effects of surfactant counter-ion.[J]. Journal of Chromatography A, 2000, 888 1-2: 229-240. DOI:10.1016/s0021-9673(00)00515-x.
[3] GARY H. PERDEW Daniel P S Henry W Schaup. The use of a zwitterionic detergent in two-dimensional gel electrophoresis of trout liver microsomes[J]. Analytical biochemistry, 1983, 135 2: Pages 453-455. DOI:10.1016/0003-2697(83)90711-X.
[4] SHINJI KONDOU. Concentrated Lithium Dodecyl Sulfate Aqueous Electrolytes: Utilizing Self-Assembly and Interfacial Adsorption for Aqueous Li-ion Batteries[J]. ChemElectroChem, 2022, 9 20. DOI:10.1002/celc.202200870.

Lithium dodecyl sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 341)
Supplier Tel Email Country ProdList Advantage
JINAN MEIGAO BIOPHARMATECH CO. LTD 13853286203 18205419756 shy96321@163.com China 20 58
Suzhou Sino Rare Chemical Co., Ltd. 0512-62857507 sales@sinorarechem.com China 999 58
Wuhan kemike Biomedical Technology Co., Ltd 027-87747081 18186681184 1344475572@qq.com China 6944 58
Shaoguan Gaokexiang High-tech Material Co.,Ltd. 15089879907 info@gkstech.cn China 129 58
Qingdao Port Liwei Import and Export Co., Ltd 13853286203 13853286203 shy96321@163.com China 40 58
Shanghai Yihe Biological Technology Co., Ltd. 021-68882955 17721395025 2423903095@qq.com China 5000 58
Jiangsu Runfeng Synthetic Technology Co., Ltd. 0513-66017678 18551497631 507167383@qq.com China 4976 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69

View Latest Price from Lithium dodecyl sulfate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lithium dodecyl sulfate pictures 2026-09-24 Lithium dodecyl sulfate
2044-56-6
1kg 99.52% 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
Lithium Dodecyl Sulfate pictures 2026-03-25 Lithium Dodecyl Sulfate
2044-56-6
$15.00 1kg 97% 50 tons Aurora Industry Co., Ltd.
Lithium Dodecyl Sulfate pictures 2026-03-20 Lithium Dodecyl Sulfate
2044-56-6
$1.00 1kg 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
LITHIUM DODECYL SULFATE (LAURYL SULFATE LITHIUM SALT) Lithium dodecyl sulphate >98% LITHIUM LAURYL SULPHATE extrapure Dodecyl lithium sulfate, Dodecyl sulfate lithium salt, Lauryl sulfate lithium salt, Lithium lauryl sulfate LiDS Sulfuric acid lauryl=lithium salt Sulfuric acid lithium dodecyl ester salt LITHIUMDODECYLSULFATE,ULTRAPURE LithiuM dodecyl sulfate, 99+% 25GR LithiuM Dodecyl Sulfa LithiuM dodecyl sulfate (LDS) LithiuM dodecyl sulfate, Min. 98% LithiuM Dodecyl Sulfate [for BiocheMical Research] 4-cyclohexylphenyldiphenylsulfoniuM nonaflate LITHIUM DODECYL SULFATE LITHIUM DODECYL SULPHATE LITHIUM LAURYL SULFATE Laurylalcoholsulfate,lithiumsalt BRAND? press-on lid for urine beaker Press-on Lids BRAND? desiccator ′Novus′ lid with socket NS 24/29 BRAND? desiccator ′Novus′ lid with knob BRAND? push-on lid for buckets BRAND? lids for microplates BRAND?plates Lithium dodecyl sulfate Vetec(TM) reagent grade, >=98.5% Sulfuricacid,monododecylester,lithiumsalt LAURYL SULFATE LITHIUM, MOLECULAR*BI LAURYL SULFATE LITHIUM SIGMAULTRA DODECYL LITHIUM SULFATE DODECYL SULFATE LITHIUM SALT DODECYL SULPHATE, LITHIUM SALT LAURYL SULFATE LITHIUM SALT LAURYL SULPHATE, LITHIUM SALT LAURYL SULFATE LITHIUM ELECTROPHORESIS*R EAGENT LAURYL SULFATE LITHIUM, MOLECULAR*BIOLOG Y REAGENT Lithium dodecyl sulfate, 99+% lithium(1+) dodecyl sulfate 2,4,6-trimethylbenzyl 2,4,6-trimethylbenzoate LITHIUM DODECYL SULFATE ISO 9001:2015 REACH Dodecylsulfuric Acid Lithium Salt Laurylsulfuric Acid Lithium Salt ithium dodecyL LithiumDodecylSulfate[forBiochemicalResearch]> Sulfuric acid, monododecyl ester, lithium salt (1:1) Lithium dodecyl sulfat LITHIUM LAURYL SULPHATE High purity lithium dodecyl sulfate Lithium dodecyl sulfate, Anionic detergent Lithium DodecyI SuIphate(LDS) hMAD-3 hSMAD hSMAD3 JV15 MAD homolog MAD homolog 3 Mothers against decapentaplegic homolog Mothers against DPP homolog SMAD family member